The Creepy Candy Coating Corollary - S3-E5
Continuity mistake: Bernadette speaks regular here. In future episodes she suddenly has a higher-pitched voice.
Suggested correction: This isn't really so much a mistake as it was a character tweaking, which happens often in TV series.
The Dead Hooker Juxtaposition - S2-E19
Continuity mistake: After the guys leave and Penny and Sheldon are eating alone, Sheldon's chopsticks switch between an unevenly broken pair of chopsticks and an evenly broken pair of chopsticks.
The Big Bran Hypothesis - S1-E2
Continuity mistake: When Sheldon is cleaning, he moves an iPod dock and the iPod lights up. Camera changes and the iPod is unlit. A few shots later it's lit again. (00:09:00)
The Proposal Proposal - S11-E1
Continuity mistake: When Penny and Bernadette are talking in the kitchen, the string for the teabag in Bernadette's yellow mug keeps moving between shots.
The Panty PiƱata Polarization - S2-E7
Continuity mistake: When Leonard talks to Penny about having to live with Sheldon he has his hand up to his chest. Camera swaps to a side view and his hand is not in front of his chest any more. (00:07:30)
The Griffin Equivalency - S2-E4
Continuity mistake: When Raj asks the guys who's going to the party on Saturday night, Penny's grip on the martini glass she has changes between shots. (00:10:20)
The Barbarian Sublimation - S2-E3
Continuity mistake: When Penny explains she has bought the game, her grip on the laptop changes. (00:06:50)
The Barbarian Sublimation - S2-E3
Continuity mistake: At the start, after Penny has dropped one bag, there is an item in the top of the remaining bag. This item keeps appearing and disappearing. (00:01:20)
Continuity mistake: When Leslie and Leonard are talking about starting a relationship again, the can of Diet Cola keeps rotating. In some shots from Leslie's point of view you can't see the logo and in others you can. (00:06:30)
Continuity mistake: When Leonard says he is happy Penny is moving on he has nothing in his hand. Camera cuts and now he is holding a bit of bread. (00:03:00)
Continuity mistake: When Sheldon is undoing a pair of socks that Penny has paired, Penny is seen holding a single sock. Camera changes and she now has nothing in her hands. This is an instant cut. No time to drop it. (00:05:50)
The Recollection Dissipation - S10-E20
Continuity mistake: When Howard and Bernadette are talking in the kitchen by themselves, Howard's bottle of water keeps moving between shots.
The Escape Hatch Identification - S10-E18
Continuity mistake: Stewart eats a ham sandwich when he and Raj are talking alone in Howard's and Bernadette's living room. On at least one occasion the sandwich's size gets larger, not smaller between bites as Stewart is eating it.
The Ornithophobia Diffusion - S5-E9
Continuity mistake: When Leonard and Penny are at the movie theater the same couple walks behind Leonard, twice.
The Fetal Kick Catalyst - S10-E6
Continuity mistake: Near the end of the episode where Sheldon and Stuart are drunk and talking about how Sheldon never leaves the house without a paperclip, the amount of Mimosa in their glasses suddenly decreases between shots.
The Brain Bowl Incubation - S10-E8
Continuity mistake: When Raj puts down the rubber gloves when talking with Isabella, the gloves completely vanish 6 shots later with nobody touching them.