The First Pitch Insufficiency - S8-E3
Continuity mistake: When Howard is on the mound, the shot from behind the plate shows a player ready to catch the ball in a uniform shirt. The next long shot from the stands shows a catcher in full gear, and then back to behind the plate to the player in uniform shirt only.
The Comic Book Store Regeneration - S8-E15
Continuity mistake: While in Penny's apartment, Sheldon is folding laundry and Penny is talking to him from the kitchen counter. Between shots, the water bottle in front of Penny moves by itself to different spots on the counter.
The Troll Manifestation - S8-E14
Continuity mistake: When the gang and Stephen Hawking are video chatting, the Android mascot is lying down when the camera is facing the gang, but when the camera is facing Stephen Hawking, the Android mascot is standing up.
The Comic Book Store Regeneration - S8-E15
Continuity mistake: While Bernadette is talking with Howard about Stuart living in Mrs. Walowitz's home, she is taking items out of a grocery bag. One of the bags of food changes spots on the table in the next shot.
Continuity mistake: In this episode Leonard has a snoring problem (a result of a deviated septum, which in all probability he was born with, plus Amy says Sheldon has always complained about Leonard's snoring, and Sheldon says after 5 or 6 years he's gotten use to Leonard's snoring), but in episode 14 of season 3 when Sheldon brings up snoring Penny says, "Leonard doesn't snore." And in episode 8 of season 6, Sheldon lists not snoring as one of Leonard's positive traits.
Suggested correction: Genes can be dormant. Which allows them to skip generations. Therefor Missy's children could actually get the "mutated" gene. This is especially true since Sheldon and Missy are twins. Also, since the episode is about who out of Leonard, Howard or Raj, Sheldon would allow to "mate" with his sister, there is the added "insurance" of getting any smart genes from any of the 3 Lothario's mentioned above.
If you are going to try to argue with a geneticist about genetics, please use the correct terms. Sheldon is not referring to a recessive gene - there is no such thing as a dormant gene - he is speaking of a randomly mutated gene. Those are the words he used. If he had inherited a homozygous recessive karotype - one recessive gene from each of his parents - then somewhere in his family tree there would similarly gifted people, in which case he would use the correct term - a recessive gene. If Missy is a heterozygotic dominant karotype possessing the recessive gene for super-genius and the dominant for ordinary intelligence then mating her with Howard, Raj or Leonard would be a waste of time as their dominant genius gene would prevent the recessive super-genius gene from being expressed in the phenotype of the resulting child. The child would be highly intelligent but not on Sheldon's standards. It doesn't matter if Sheldon does not know any of this as he refers several times to a randomly mutated gene, not a recessive one. Missy does not carry the super-genius gene. The posting is correct.
Sheldon is prone to magical thinking when necessary to preserve his obsessive need to control his environment. He may have simply ignored the flaw in his reasoning, as even the most intelligent humans do when venturing outside their ares of expertise. He may be interested in the science of genetics, but his Ph.D. in physics doesn't qualify him as an expert in that field.