Starring: Kaley Cuoco, Johnny Galecki, Melissa Rauch, Simon Helberg, Jim Parsons, Kunal Nayyar
Genres: Comedy
The Spoiler Alert Segmentation - S6-E15
Revealing mistake: Throughout the series much is made of the fact that Howard's mother is grossly obese, and in The Engagement Reaction (S4 E23) it is even mentioned that her arms are hugely oversized. However, at the end of this episode we see her arms when she grabs Raj to stop him climbing out of the window, and they are the arms of an average-weight woman - they aren't overweight at all.
The Countdown Reflection - S5-E24
Factual error: There is not a snowball's chance of Howard becoming an astronaut. He suffers from cardiac arrhythmia, something about which he is completely open. "Transient" or not this is easily detectable by a simple electrocardiogram, which is a fundamental part of the many medical examinations a potential astronaut will have to pass. He wouldn't even be allowed to start basic training. Note also that during his basic training he shows signs of severe stress and trauma which would inevitably trigger a cardiac episode. Even if it didn't the fact that he was falling apart at the seams would have him removed from the programme for his own good.
The Staircase Implementation - S3-E22
Leonard: Oh, screw the roommate agreement!
Sheldon: No, you don't screw the roommate agreement! The roommate agreement screws you!
The Work Song Nanocluster - S2-E18
Trivia: After Sheldon mentions a molecular sieve, they go over to 4a, their apartment. 4a is a kind of molecular sieve.
The Euclid Alternative - S2-E5
Question: Though it comes up in other episodes as well, this one is focused on Sheldon needing a ride everywhere he goes because he can't drive, not to mention his not being welcome on the bus. Of course, this story element would be nonexistent if there was a simple answer, but it does beg the question: Does Pasadena not have taxicabs?
Answer: Sheldon DID finally use a taxi when going to the airport to see and propose to Amy in New Jersey.
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Chosen answer: It does. The variable cleanliness of the cab and the habit of taxi drivers to engage customers in small talk would be too much for Sheldon to handle, and not an option for him.
Captain Defenestrator