The Luminous Fish Effect - S1-E4
Continuity mistake: When Penny comes into the apartment to ask if Sheldon needs anything from the market, between the few shots, the position of the napkin and the pile of eggs on the plate he is holding changes. (00:05:15)
The Luminous Fish Effect - S1-E4
Continuity mistake: When Leonard and Sheldon are walking downstairs, Sheldon stops and pins back up the caution tape that is in front of the elevator. Between shots, the other strip of caution tape untwists itself. (00:01:25)
The Luminous Fish Effect - S1-E4
Continuity mistake: When Sheldon's mom is saying the prayer, the bread roll that Raj is holding swaps hands, and then it disappears in the shot where she tells them they don't have to join in with the end of the prayer.
The Luminous Fish Effect - S1-E4
Continuity mistake: When Penny is asking if Sheldon has ever done anything like this before she is holding her plate with 2 hands in one shot and 1 hand in the next. (00:13:20)
The Luminous Fish Effect - S1-E4
Continuity mistake: When Sheldon asks his mum why she's there, his mums hand on his chest changes position. Note the distance to his elbow. (00:11:40)
The Luminous Fish Effect - S1-E4
Continuity mistake: At the buffet, Sheldon has 2 hands on his plate. Camera cuts and now he has one hand by his side. This is before Howard walks in with his date. And the cut is instant. (00:02:00)
Suggested correction: Genes can be dormant. Which allows them to skip generations. Therefor Missy's children could actually get the "mutated" gene. This is especially true since Sheldon and Missy are twins. Also, since the episode is about who out of Leonard, Howard or Raj, Sheldon would allow to "mate" with his sister, there is the added "insurance" of getting any smart genes from any of the 3 Lothario's mentioned above.
If you are going to try to argue with a geneticist about genetics, please use the correct terms. Sheldon is not referring to a recessive gene - there is no such thing as a dormant gene - he is speaking of a randomly mutated gene. Those are the words he used. If he had inherited a homozygous recessive karotype - one recessive gene from each of his parents - then somewhere in his family tree there would similarly gifted people, in which case he would use the correct term - a recessive gene. If Missy is a heterozygotic dominant karotype possessing the recessive gene for super-genius and the dominant for ordinary intelligence then mating her with Howard, Raj or Leonard would be a waste of time as their dominant genius gene would prevent the recessive super-genius gene from being expressed in the phenotype of the resulting child. The child would be highly intelligent but not on Sheldon's standards. It doesn't matter if Sheldon does not know any of this as he refers several times to a randomly mutated gene, not a recessive one. Missy does not carry the super-genius gene. The posting is correct.
Sheldon is prone to magical thinking when necessary to preserve his obsessive need to control his environment. He may have simply ignored the flaw in his reasoning, as even the most intelligent humans do when venturing outside their ares of expertise. He may be interested in the science of genetics, but his Ph.D. in physics doesn't qualify him as an expert in that field.