The Hawking Excitation - S5-E21
Continuity mistake: Penny is talking to Sheldon in the laundry room and places a box of detergent on the machine. The side of the box is facing her. In the next shot, the box has turned to face her.
The Russian Rocket Reaction - S5-E5
Continuity mistake: In the scene where Howard and Bernadette are about to have sex and Bernadette leaves to "brush her teeth", Howard stretches and lays on the bed uncovered. After Howard's mother yells "over my dead body my son goes to space" and Bernadette appears again and says "I'm ready", then it flashes back to Howard and he is instantly covered up.
The Precious Fragmentation - S3-E17
Continuity mistake: When Sheldon sneaks into Leonard's bedroom while Leonard and Penny are sleeping, Penny has her arms out over the blanket and Leonard has his on his pillow in front of his face. When Sheldon leans over Penny only her hands are on top of the covers and Leonard's are tucked under his pillow.
Continuity mistake: When Penny is talking to Leonard about who read her Ex's blog, she has a spoon full of ice-cream. Camera cuts and it's now empty. (00:05:00)
The Launch Acceleration - S5-E23
Factual error: In all the episodes leading up to Howard and Bernadette's wedding, Howard was going into space to install a space toilet. But in this episode, Howard tells her they want his telescope, so he has to go.
Suggested correction: The space toilet was something Howard designed that NASA installed back in season 2. His mission to the ISS in season 5 was always about his telescope. In episode 5, "The Russian Rocket Reaction", Howard says NASA picked his team's design for the deep field space telescope that's going on the International Space Station in the spring.
The Proton Displacement - S7-E7
Character mistake: When Raj shows Penny, Amy, and Bernadette how to make jewelry, Penny keeps having trouble with the glue and gets it all over her fingers. However, in Season 2, episode 5, she has no trouble at all with the glue when making 1000 Penny Blossoms.
The Speckerman Recurrence - S5-E11
Character mistake: Throughout the show, Sheldon denounced his mother's religion and God. To the extreme. In this episode, he said, "More sense than God gave a mouse." He would never invoke God for any reason.
The Big Bran Hypothesis - S1-E2
Character mistake: Sheldon does not do his 3x OCD knock on Penny's door.
Suggested correction: That quirk wasn't brought into the series until halfway through the first season. The one-knock Sheldon happened a couple of times before it became the three knock habit.
The Creepy Candy Coating Corollary - S3-E5
Other mistake: When Sheldon signs the entry sheet Stuart claims he wrote "Die Will Wheaton Die." But he was only writing for half a second to a second, he could never have written all that in the time frame.
The Prestidigitation Approximation - S4-E18
Continuity mistake: It is well-known that Leonard's glasses do not have lenses to avoid catching reflection by the lights. In this episode, Priya takes Leonard's glasses off, and they have lenses.
The Extract Obliteration - S6-E6
Continuity mistake: Sheldon is siting at the kitchen counter with a mug in front of him. In one shot, the string of a teabag appears coming out of the mug. In between shots, the teabag string moves by itself.
The Robotic Manipulation - S4-E1
Continuity mistake: At the start, as Howard says "And finally my kung pow chicken" the robot arm is level with the top of the bag. Camera cuts and it's reaching to the bottom of the bag. (00:00:15)
The Classified Materials Turbulence - S2-E22
Continuity mistake: Leonard is talking to Stuart at the door to his (Leonard's) apartment. Howard then comes over and slams the door in Stuart's face and Leonard has moved back about 4-ft instantly.
The Lizard-Spock Expansion - S2-E8
Continuity mistake: The way Leonard holds the can of Diet coke before he puts it down changes between shots. (00:00:25)
The Matrimonial Momentum - S9-E1
Continuity mistake: In the first half of the episode while in Las Vegas, Penny's hair is short; however, later in the episode when she is back in the apartment speaking with Sheldon, her hair is much longer, albeit tied back in a bun, but very obviously much longer and a very different color. The scene from Las Vegas to her apartment was less than 24 hours apart and would have been impossible for her hair to have grown so much.
The Hot Troll Deviation - S4-E4
Continuity mistake: When Sheldon and Raj are arguing about having a desk in Sheldon's office, Sheldon's bottle of water keeps rotating without anyone touching it - take note of the label. The level of water in Sheldon's drink also keeps changing between shots. (00:06:20)
The Robotic Manipulation - S4-E1
Continuity mistake: When driving to the date, the cars behind Penny's change place instantly. For example a 4x4 becomes 3 cars, which become 1 car in the space of 3 seconds. (00:09:10)
The Bath Item Gift Hypothesis - S2-E11
Continuity mistake: When Penny takes a drink from the egg-nog carton before kissing Leonard on the cheek, between shots the logo-branded label changes which direction it faces in her hand. (00:16:45)
The Vartabedian Conundrum - S2-E10
Continuity mistake: When Stephanie asks Leonard why he hasn't told her about Penny, he spills some of the pancake mixture out of the bowl he is stirring. In some shots the spilled mixture vanishes and the appears again.
The Maternal Capacitance - S2-E15
Continuity mistake: After Leonard's mother says, 'Tell me about it', her head was tilted downwards, but in the next shot, she was looking straight again. (00:04:35)
