Continuity mistake: In Season 2: Episode 9-"Unearthed" when Bellick is talking to T-Bag in the house, he pulls up a chair to sit down in front of T-Bag. When he pulls the chair out and starts to sit down, the chair is backwards, but in the next shot it's facing T-Bag. (00:38:10)
Factual error: Michael and Lincoln are seen in the morning at 9 am in Montana (between Great Falls and Helena). Later in the show, the next day at 12.50 am, they are trying to meet with Sarah in Akron Ohio. That is a 33-hour drive from Helena.
Continuity mistake: Season 2, Episode 10. When Michael and Sara are driving towards Mahone down Butterfield Road, both cars are seen in one shot and both cars are on a gravel road. In the next clip, seen from Mahone's end of the road, his car is on asphalt.
Revealing mistake: In the episode where Scofield, Sucre and T-Bag are driving in Panama, the trees in the background have no leaves - like Autumn/Winter in the US. And even though there of course are trees in Panama which shed their leaves, there is no time of year when all trees are leafless - like in the temperate zones. That shot was definitely not filmed in Panama.
Continuity mistake: Series 2 - Episode 10. When Sara is to meet Michael at 1681 Butterfield Road Sara looks in the mailbox. She closes the lid, yet the mailbox is seen standing with the lid a bit open. In the next couple of shots the mailbox is completely open, and when they jump in the car and leave, the lid is now closed.
Continuity mistake: In the scene in Panama in the last episode Michael is on the boat and a boy comes along with some sodas. In that scene the sky is overcast. But in the next clip, when the boat is seen further away the sky is clear.
Continuity mistake: Episode 14 - John Doe. Bellick is in the prison, and is being threatened by 'Banks.' As Banks and his crew walk away, in two different shots, you can see an elderly gentlemen (looking like Charles Westmoreland) walk across the screen, left to right. He does this twice, without there being time for him to run around.
Other mistake: Near the start of the season Lincoln gets a bullet wound to his leg, However there is no exit wound, revealing the bullet is lodged in his leg. Yet he is able to run and move around with relative ease just hours after being shot.
Revealing mistake: When 5 of the escapees are heading to Oswego to get the supplies and Michael tells Lincoln to turn right, you can see it isn't a real car as the steering wheel doesn't turn - Lincoln just moves his hand along the wheel. Watch the grooves and you will see. (00:18:50)
Continuity mistake: When Mahone is in Scofield's apartment the show flashes back to an overhead view of Scofield planning on the wall while Mahone is tracing over the holes in the wall from where Scofield was tacking papers up. The mistake is in the flooring, the laminate flooring is a much lighter flooring than when Scofield was there two months prior. (00:21:00)
Continuity mistake: When Steadman takes out his gun, he presses it to the back of Veronica's head. She does not flinch or shy away from the gun, but in the next shot, a close-up of Steadman, the gun muzzle is pointed at the camera with Veronica off-screen, and so the gun is suddenly not touching her. (00:22:40)