Revealing mistake: When they show the soldiers killed by the Dalek, in both the hallway outside the cage and the large room in weapons testing, they show some casings which were ejected from the soldiers' guns. The casings still have projectiles in them. If used, they would have been in magazines and would never fall out like they are shown.
Revealing mistake: When the alien spacecraft crashes into Big Ben, it is obvious that the shot has been reversed/flipped around. Look at the Roman numerals on Big Ben's clock face: They should read (clockwise from the top) XII, I, II, III, and so. Instead they read IIX, IX, X, etc. (00:06:35)
Revealing mistake: The 'earthquake' that takes place in this episode results in CGI-created cracks in the pavement that are very unconvincing. They do not appear to displace anything and - in a related continuity error - the cracks disappear in shots taken from ground level (the cracks are only visible in high-level 'looking down' shots). (00:34:30)
Revealing mistake: The Doctor and Rose locate the "metal" hatch that leads down into the Nestene Consciousness' lair. Watch carefully after the Doctor removes the "metal" hatch and moves it aside. The entire hatch pops up a second later. This is because it is plastic and it was suctioned to the floor. (00:33:06)
Revealing mistake: When Mickey closes the wheelie bin lid, he then finds the plastic stuck to his hands, he lifts his hands up and the plastic stretches like tar. If you look closely when he lifts his hands up for the first time, you'll see that a shadow of one of his hands is cast on his shirt, but there is no shadow of the strands of plastic stuck to his fingers. Additionally, when he turns around to pull away from the bin, he crosses the strands over each other, but they are still parallel in the following scene. (00:22:40 - 00:23:10)
Revealing mistake: At the end of the episode there is a side shot of the Doctor leaving the TARDIS in which you can see inside, but the control room isn't visible, just the side of the police box, with light from outside shining through the window. (00:38:00)
Revealing mistake: In close-ups of the modified pig, seams are visible on its forelimbs. (00:22:45)
Revealing mistake: There are some moments during the scene where the Doctor is being strangled by the Auton arm where it's fairly obvious that Christopher Eccleston is holding the arm to his own throat. Namely, the moments where the hand isn't quite in the right position, slipping towards his chin. (00:12:47)
Revealing mistake: Most of the time, the eyes of the dummies are molded and opaque. But in the mall, there are small holes in the eyes.
Revealing mistake: When the Editor activates the Doctor and Rose's manacles, the right manacle binding Rose's wrist snaps open as they are shocked. (00:35:12)
Revealing mistake: After the Doctor deactivates the signal hiding the Dalek fleet, when the camera zooms out to show the ships, the background image of the Horsehead and Flame Nebulae is cut off a bit below where the Dalek Emperor's flagship is shown, revealing the end of the picture they used for a background. (00:39:00)
Revealing mistake: When the Gamestation's transmissions are cut off by solar flares, there is a close-up of a screen going over to static. In the upper right corner, a box with "Play" written in it is visible, revealing the image on the screen as a video. (00:34:50)
Revealing mistake: When the Doctor fires a champagne cork into Auton-Mickey's head, the lack of spraying or leaking wine, even when the Doctor is seen holding the open bottle horizontally immediately afterwards, makes it quite clear that the champagne bottle is actually empty. (00:25:23)
Revealing mistake: In the underground scene in the Nestene lair, the CGI used to create the Nestene is horrendous. And in a shot from behind the Doctor, the Nestene looks like a whole bunch of orange pixels.
Chosen answer: 1) When Stephen Moffat took over he ignored a lot of what had been developed before (there is not in-universe answer). 2) It would have killed Rose, so the Doctor absorbed the energy. His body regenerated before the energy could do a significant amount of damage that would prevent regeneration.