Continuity mistake: During the scene where Catherine goes to her father for the money to save Nick, the character played by Frank Gorshin is talking. At one point he is seen from the front and puts his hand up to fiddle with his collar/neck. The shot changes to a side view and both of his hands are suddenly in his lap with no time for him to have put his hands down.
Big Middle - S5-E16
Continuity mistake: The board behind the oddsmaker keeps changing. At the beginning, he has crossed out the odds on the game between Miami and Memphis from 5 to 7 1/2 to 10 1/2. When Brass comes in, the board is only showing 5. It then changes every time it switches from Brass to the oddsmaker- it will show the 5 crossed out and then not crossed out the next time. Finally in the final shot, it shows the board without the 1/2 after the 10. (00:17:15)
Plot hole: The bodies were pink because of exposure to the lower temperatures created by the dry ice venting into the room. None of the CSI team noticed a chill when they entered the room? None of them noticed the bodies were cold to the touch? No one noticed that the body or liver temperatures didn't match with the estimated time of death?
Revealing mistake: When Warrick takes out the contents of the wallet, he removes a few 100 dollar bills. If you look carefully, you can see on the top bill it says "For Motion Picture Use Only."
Factual error: Brown and Stokes mix up enough ballistics gel to make a life-size dummy to test their theory. The entire production (getting a mannequin, making a mold from the mannequin, etc,.) takes place in one shift. Ballistics gel needs to cool in a fridge, or on ice, (32-41°F) overnight. That alone eliminates the possibility that it was done in one shift. http://www.recguns.com/Sources/XD3.html.
Character mistake: When Catherine is being questioned about the victim, it is mentioned that her parents were killed in an industrial accident in Odessa. To which Catherine replies, "Russia?", and is answered in the affirmative. Odessa is a major city in the Ukraine, not Russia.
Character mistake: Catherine Dent's character, Kay Marquette, plays the Holmes character Irene Adler with an English accent. Adler was an American, as mentioned by Watson in "A Scandal in Bohemia".
Continuity mistake: In the opening scene, the female student is wearing green panties. When the two bodies are found, she is wearing red panties. It was a murder behind a locked door, so no one changed them for her.
Suggested correction: The girl had green panties with pink or red strings. When she was found, all that was visible was the string.
Visible crew/equipment: When David, Warrick and Catherine are standing in the crop circle discussing how the body ended up there, when David says "I have an idea", Warrick looks up slightly and you can see the boom mike reflected in his sunglasses.
Continuity mistake: The Pontiac Fiero that is seen underneath the Hummer is a different (but newer) model than the one that was briefly seen driving away from the taco stand.
Character mistake: When Catherine slams the trash can lid shut outside and heads to the car to answer her phone, she tells her Mum 'Catherine threw something out', referring to Lindsay.
Revealing mistake: Willows discloses a laptop with the city's grid layout inside the welder's truck, and grabs her cell to call Grissom. Just as she presses last number, he immediately answers, without so much even a ring.