Pre-Witched - S3-E17
Plot hole: One of the sisters asks why the familiar doesn't just jump in front of a bus 5 times, another responds with "we're the only ones strong enough to kill him." If they are the only ones strong enough to kill him, then how come two scenes later he falls on a knife during a fight with Phoebe and dies? If a knife can kill him then it doesn't make sense that he seeks out the charmed ones.
Answer: That was a mistake in the series.
Also, the episode is called 'Babies First Demon' and this alone tells us that it's Wyatt's first time in the field (so to speak) and as the sisters say, they've done a good job of clearing up their own magical messes so far. Nobody really knows how advanced Wyatt's powers are, or will become. That's why the cleaners appear, to nip things in the bud. The Cleaners didn't want to chance that the sisters could clean Wyatt's magic up, just incase they couldn't. Therefore intervening themselves, just in case.