A New World - S3-E20
Factual error: Connor has been raised since he was a few months old by Holtz, a man with a British accent, in a dimension where there are no other humans. There is no possible way he could have an American accent, yet from the moment of his return he speaks with one.
Suggested correction: The demons in Pylea spoke English with American accents (possibly due to Wolfram and Hart's interference), and in tie-in comics, demons in the dimension Connor and Holtz went to were shown speaking regular English, though these comics were released years later.
Factual error: Wesley has his throat cut, deeply enough to at least nick the artery (based on the amount of blood) and the windpipe (based on his difficulties breathing and talking later on), yet he somehow survives being left alone in the park for over 24 hours. In reality, he would have been dead long before then.