Continuity mistake: When Data is telling Guinan jokes and is then called to the bridge, he's holding the cigar between his first two fingers. In the next shot, he's holding the cigar between his thumb and first finger.
The Dauphin - S2-E10
Continuity mistake: When Wesley and Salia are on the holodeck looking at Roseau 5, Salia's left arm is around Wesley's back. In the next shot, both her hands are wrapped around his arm.
Continuity mistake: When the technician goes to revive Claire, in the long shot, her eyes open. In the close up, she "comes to" again, opening her eyes.
Continuity mistake: At the end of Barclay's sword fight on the holodeck, he has the hologram of captain Picard against a wall. When the angle is on the hologram, Barclay's sword is pressed into his chest. However, when the angle is on Barclay, the sword is several inches away from the hologram.
Continuity mistake: Near the end, when Pulaski finally stops the infection in Riker and is just about to contact Picard with her success, look at Riker lying on the table. His eyes are open, then he closes them slowly. The next scene has Riker opening his eyes for the first time after recovering from the procedure.
Encounter at Farpoint (2) - S1-E2
Continuity mistake: The computer is directing Commander Riker toward L.C. Data in holodeck area 4-J. As he walks along the corridor the computer helps him by saying that he should go to "the next hatchway on your right." Then Riker turns left (according to the way he was going) to enter the holodeck.
Continuity mistake: When alien party arrives, the turbaned assistant puts down the carpet roll the wrong way round. The next shot it is miraculously switched around so it can be rolled out towards Picard.
Continuity mistake: After Pulaski examines Riker's leg, and readies to beam up, he leans to the right to get up. In the wide shot, he does it again.
Conspiracy - S1-E25
Continuity mistake: After leaving the table in headquarters, Picard meets Riker at the door. In the far shots, Picard has his back to the table. In the close up, his left shoulder is towards the table.
Continuity mistake: William Riker is playing cards with La Forge and Worf. The camera is focusing on Riker and there is no 4th chair. When Tom Riker enters, William says "Why don't you join us" and now removes his trombone from the 4th chair which has suddenly appeared. (00:31:25)
The Arsenal of Freedom - S1-E21
Continuity mistake: As the Enterprise is attacked, the registry number is reversed.
Continuity mistake: Data's insignia pips are backwards in the first scene as he is talking to Picard on the bridge.
Continuity mistake: In the opening sequence, the ship is positioned so that Shuttle Bay Two is aimed at the phenomena. But a moment later, the ship is facing into the stellar material.
Continuity mistake: As the ship fires the torpedoes, the familiar registry number on the underside of the saucer is completely missing.
Continuity mistake: Near the end of the episode, as they are preparing to beam down to the planet, Riker tells Warf to set his phaser on stun. He then holsters his own phaser and the transporter is activated. However, when they materialize on the planet, Riker is holding his phaser in his left hand.
Encounter at Farpoint (1) - S1-E1
Continuity mistake: As Riker looks at the wooded scene on the holodeck, the water is flat calm, but when the camera looks at him, the water is noticeably more agitated before he gets to the rocks.
Continuity mistake: As Geordi talks to Ms. Rogers, Riker is walking in the background by some containers and a crewman in blue. After a cut to Ms. Rogers, Riker is suddenly alone with a data pad.
Answer: He brought the Borg to the Alpha Quadrant and showed them that it was full of worlds waiting to be assimilated. Guinan's homeworld was their first stop, and they assimilated everyone and took over the planet, leaving The Survivors of her race without a home. Q is ultimately responsible for that.
Captain Defenestrator
By the time Q takes the Enterprise to meet the Borg, Guinan already knew who they were and they had already destroyed her world. Therefore the above answer can not be right. I believe Guinan is much more than she appears, and her people have had encounters with the Q in the past. It is these interactions, that obviously were not pleasant, that fuels her distrust.
oldbaldyone
That's what the above answer is saying. Q brought the Borg to the Alpha Quadrant (not Earth) and the Borg destroyed Guinan's home world in the late 2200's, which is why she hates Q. Although she met Q in 2160 and they both saw each other as enemies right away.
Bishop73