Two Birds of a Feather - S3-E19
Factual error: No matter how good of a pilot Samuel is, he's chasing a Learjet 24 plane with a WWII design P-51 Mustang (that he does not even know how to start, but of course fictional pilots can just 'wing it' and do amazingly). Assuming that speed is not a factor since the bad guy is not flying at top speed just yet (but still he has a projected arrival time of 6 hours, meaning he'd fly around 700 kmh), they do the chase at high altitude (42,000 feet are mentioned), with Samuel not wearing a mask or anything in a non-pressurized plane! He'd have passed out.