Other mistake: Bruce is seen wearing a Polar F5 heart rate monitor in a couple of scenes after Betty gives it to him (such as when he is in bed with Betty) but there is no transmitter strap around his chest, which that model needs in order to pick up the wearer's heart rate.
Other mistake: When Bruce is riding his bicycle to deliver pizza to the University, you hear him ringing a bicycle bell while he says, "Excuse me". If you look at the bike he's riding, there's no bell to be found. (00:36:00)
Other mistake: In the University battle sequence, the screen shot of the attacking helicopter's targeting system indicates a lock on the Hulk, but when the pilot opens fire, the machine gun bullets "walk" to their target, instead of being direct hits as would be expected.
Chosen answer: It's entirely self-containing - effectively the film acts as a relaunch of the franchise rather than a continuation, although it doesn't really have any continuity issues with the first.
Tailkinker ★