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Continuity mistake: Alice jumps up to avoid the laser at the very start and the laser cuts part of her dress off that is to fall to the floor. However when she lands the separate part is not on the floor where it should be. (00:03:30)
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Continuity mistake: At the start, the trolley gets cut in half and Alice isn't stood near either of the two halves. When she starts walking off she's next to part of the trolley. (00:04:10)
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Continuity mistake: At the start, the woman falls to the floor and you can see her kneepads under her trousers. (00:04:15)
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Revealing mistake: When the woman is attacked by the dogs you can see the protective padding on her arms where the dogs bite her. (00:04:15)
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Revealing mistake: When the blade cuts the trolley in half, the blade hits the top of the trolley but the metal frame of the trolley is to break in a perfect cut. (00:04:30)
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Visible crew/equipment: After the first Alice clone dies in the movie and Dr. Issacs takes off his helmet, look at the scientist to HIS right(our left) you can see the boom operator in his reflective mask along with the camera operator. (00:04:50)
Other mistake: In the scene where Dr. Isaacs is in the teleconference with the Umbrella Board of Directors, there are several glasses of water sitting in front of each individual hologram. At the end of the teleconference, the holograms of the board members disappear, but none of the glasses follow suit. This tells us that the glasses of water were physically in the room with Dr. Isaacs, for absolutely no reason, given all the other attendees weren't really there. (00:17:40)
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Revealing mistake: When Stevie is looking around in the desert before being shot, you can see the outline of his facial makeup around his eyes. (00:17:50)
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Continuity mistake: When Stevie is against the truck, his head is tilted to his left while impaled. But in the close up of him being impaled his head is looking straight ahead. (00:18:30)
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Continuity mistake: When Stevie is impaled on the abandoned truck, he's seen in a strip of shade, when Alice walks over the strip of shade has gone. (00:18:30)
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Continuity mistake: When Stevie is shot, there is blood spatter on the truck. When we see the close up of him the blood spatter has gone. (00:19:00)
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Continuity mistake: Alice exits from the gas station and gets on her bike to read the book she obtained inside the gas station. However we see her looking at a page with a picture and the word "Isolated" on it. When the camera changes and she is closing the book it's on a different page. She's not changed the page as it's audible when she does and the sound is missing. (00:20:15)
Revealing mistake: When the truck approaches the motel, tyre tracks are visible in the dirt exactly where the truck will drive. (00:21:50)
Deliberate mistake: During the scene where Carlos and L.J. are searching the motel, L.J. sees a zombie which turns out to be a reflection in a wall-length mirror. L.J. shoots, breaking the mirror and realizing his mistake. But, if he had been standing in front of the mirror as shown, he should have seen his own reflection standing there as well. This was done as an homage to a similar encounter in the original game. (00:24:20)
Continuity mistake: When Dr. Isaacs is injecting a zombie with his domestication serum, the head restraint on the zombie disappears. (00:26:10)
Continuity mistake: When Dr.Isaacs is injecting a zombie with his domestication serum, he changes positions from being beside the zombie, to being on the opposite side of the table. (00:26:10)
Visible crew/equipment: When Alice is walking in the desert after her bike brakes, the shadow and edge of some filming equipment can be seen in her reflective glasses. It can't be her shadow as that's seen behind her in other shots. (00:33:44)
Revealing mistake: We see LJ and the lady holding the glass windscreen of the bus to stop the birds from getting in. However it's clear to see the glass and birds are CGI as the hands appears to float on the glass. (00:37:20)
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Continuity mistake: Betty gets attacked by the birds and ends up with blood all over her face. When she shuts herself in, the blood is all gone and her face is clear. (00:39:00)
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Factual error: The sign in Vegas has the wrong wording. It says "welcome to the fantastic Las Vegas" instead of "Welcome to the Fabulous Las Vegas". (00:51:10)