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Revealing mistake: When the convoy is on the way to Vegas, tyre marks can be seen in the sand ahead of the convoy possibly from previous takes. (00:51:50)
Factual error: In Las Vegas Paris and The Vencian are not next to each other. They farther part then that. Next to Paris is Ballys. (00:53:10)
Other mistake: As Chase pulls the tanker to a stop in Vegas, the engine revs once more before it's shut down, but the rain caps don't pop up as they should from the extra puff of exhaust. (00:54:50)
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Plot hole: When the survivors arrive in Las Vegas, all that is visible is the Strip. No other buildings are seen, even though Las Vegas has other high-rise buildings that are not on the Strip, and the level of sand that has built up is not substantial enough to have buried the entire city. (00:55:00)
Deliberate mistake: The zombies are to exit from a standard 40ft shipping container in Vegas. When we see the shot of Alice and co from inside the container you can see that up to 1/4 of the container contains no zombies. However when released, the amount of zombies seen is far more than what could have fitted into the remaining space of the container. (00:56:50)
Continuity mistake: After the Zombies are unleashed in the desert scene, we see Carlos crawling under the truck. At first his semi-automatic gun seems to be completely normal. The gun's slide and chamber are closed as if there are still bullets in the magazine or at least one bullet is chambered. But then the camera focuses on his gun and we see the gun's chamber is open - as if there are no bullets left. The gun didn't fire between shots so it's chamber should have been open in the first place. (00:58:10)
Revealing mistake: As the mutated zombies chase some of the survivors up the cement ramp in Las Vegas, watch the very last zombie just behind the girl in the tank top. He slows himself down to a fast walk when the actress starts running too slow. (00:59:40)
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Continuity mistake: Carlos dives under his truck and finally shoots the two zombies in the head and his scarf is not around his mouth. As the camera changes, it suddenly is. (00:59:45)
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Revealing mistake: We see Claire loading her weapon when Mikey is being attacked. However if you watch closely you will see she is loading blanks into the weapon. (01:01:40)
Continuity mistake: When Chase falls off the Eifel tower, there is an overhead shot where it shows he's got a clear path to the sand. However he lands on part of the structure. (01:03:00)
Continuity mistake: When Project Alice starts to fight the control of Umbrella she jumps off a wall. In the first frontal shot her coat is flowing freely behind her. But in the second shot, it's wrapped around her leg. (01:03:30)
Continuity mistake: In the scene where Dr. Isaacs escapes from Alice in a AS350B Eurocopter, we see that the helicopter's landing gear has an additional iron bar that has been changed from one scene to another. When the helicopter lands in the desert, the bar is missing. So Dr. Isaacs flew away in one helicopter and landed in another. (01:04:00)
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Continuity mistake: When Claire approaches Alice who is watching Issacs fly away, Claire has her hands behind her back in one shot and up at her face in another. (01:05:00)
Character mistake: Alice shoots the henchmen, the black officer is attempting pull a gun from his shoe but in closeup his leg is white, then back. (01:06:25)
Revealing mistake: As Carlos is giving his final goodbyes to Claire you can see in the background automobiles driving down the freeway. Shouldn't these roads be empty rather than having what seems to be a thriving highway? (01:10:00)
Suggested correction: Not a single car in the background.
Continuity mistake: When the tanker explodes that Carlos jackknifes at the end scene, the zombies that surrounded the tanker simply fall over from the explosion. However when Alice drives the H2 up to and through the wreckage the ground is clear of any fallen bodies. (01:10:50)
Plot hole: In the scene where Alice breaks into the Umbrella compound she drives the vehicle through the truck wreckage and into the fence, knocking the fence down. However, she then has time to ferry everyone from the vehicle into the chopper, stand back and watch them fly away, then walk cautiously into the shanty shack and wait for the elevator to arrive. Meanwhile not a single zombie has chased her into the now breached compound. The zombies might be dumb, but if they see food they head straight to it until an obstacle stops them and the explosion would have only killed the ones in the immediate area. The ones behind the dead zombies would have charged at them as soon as the fire died down. (01:11:00)
Revealing mistake: After Carlos blows his truck up and Alice is breaking into the Umbrella compound there is a moment where her truck drives through the fire and one of the zombies following her throws his arms up to shield himself from the heat of the flames. The actor apparently got too close for his own comfort. (01:11:00)
Continuity mistake: Alice steps into the entrance to the hut with her right foot in one shot and her left in the following shot. (01:12:50)