Plot hole: When the umbrella ops first get onto the train, rain has to power it up. There were plugs disconnected, and you see a hole in the fence as she shines a flashlight on it. It can't be anything infected because they didn't power down the red queen yet, and release the bioweapons. The red queen isn't physical, just controls systems. And with none of the zombies, or other infected loose yet, what else could have unplugged it? Spence was knocked out on the train, this seems to be a plot hole. (00:02:00 - 00:20:10)

Resident Evil (2002)
1 plot hole - chronological order
Directed by: Paul W.S. Anderson
Starring: Milla Jovovich, Michelle Rodriguez, James Purefoy, Colin Salmon, Anna Bolt, Indra Ové, Joseph May, Oscar Pearce, Ryan McCluskey

Continuity mistake: Near the beginning of the movie, Milla Jovovich reads a note that has been left on the desk. She didn't write it, as they demonstrate in the film. However, when they do show the person who wrote the note composing it, the handwriting is different from that in the note from the earlier scene. (00:10:20 - 01:12:25)
Trivia: The train which the heroes catch to and from the umbrella facility is remarkably similar to the train at the end of the Resident Evil 2 game.
Question: Is the reanimation of dead people the purpose of the virus, or an unforeseen side effect? If it's a side effect, what was the original purpose of the T-Virus?
Answer: The original virus was a "Fountain of Youth" type of thing. Reviving dead cells so the host would stay young. It was so powerful that it reanimated the dead.
Answer: Wait, wasn't the original virus meant to control the scientists daughters genetic disease, not an eternal life serum.





Answer: Actually the T-Virus was originally meant as a cure for a genetic disorder that Dr. Ashford and James Marcus daughters suffered from. The reanimation was a side effect and James Marcus was killed by Dr. Alexander Isaacs so he could take control of it and turn it into a bio-weapon.
lionhead