Plot hole: When the umbrella ops first get onto the train, rain has to power it up. There were plugs disconnected, and you see a hole in the fence as she shines a flashlight on it. It can't be anything infected because they didn't power down the red queen yet, and release the bioweapons. The red queen isn't physical, just controls systems. And with none of the zombies, or other infected loose yet, what else could have unplugged it? Spence was knocked out on the train, this seems to be a plot hole. (00:02:00 - 00:20:10)
Resident Evil (2002)
1 plot hole - chronological order
Directed by: Paul W.S. Anderson
Starring: Milla Jovovich, Michelle Rodriguez, James Purefoy, Colin Salmon, Anna Bolt, Indra Ové, Joseph May, Oscar Pearce, Ryan McCluskey
Continuity mistake: When Matt gets scratched by the mutated Licker at the end of the film, the scratches on his arm appear before the creature's claws actually hit him. (01:24:15)
Red Queen: You're all going to die down here.
Trivia: The train which the heroes catch to and from the umbrella facility is remarkably similar to the train at the end of the Resident Evil 2 game.
Question: Why is the game series this is based on known as 'Resident Evil' in some countries but in others it's called 'Biohazard'? Does the name swap also apply to the film?
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Answer: The game was originally called 'BioHazard' in Japan, but because of copyright problems with the band Biohazard, was named 'Resident Evil' in the US and Europe. However most hard-core gamers call it 'BioHazard' no matter where they live. For more info, check out http://faqs.ign.com/articles/378/378719p1.html.