Continuity mistake: Near the end of the film, on the train ride out of the Hive, Rain is quite close to becoming undead. When she speaks, we notice her teeth are still "movie-star white". However, a few shots later, when she becomes a zombie, she sort of hisses where you can see it has taken what couldn't have been more than a few mere minutes for her teeth to become brown and discolored. (01:21:00)
Continuity mistake: Near the beginning of the movie, Milla Jovovich reads a note that has been left on the desk. She didn't write it, as they demonstrate in the film. However, when they do show the person who wrote the note composing it, the handwriting is different from that in the note from the earlier scene. (00:10:20 - 01:12:25)
Continuity mistake: When Matt gets scratched by the mutated Licker at the end of the film, the scratches on his arm appear before the creature's claws actually hit him. (01:24:15)
Other mistake: When we see the numbers for the coded entry to Alice's weapon, the order of the numbers is 1 - 2 - 3 - 4 - 5 - 6 - 7 - 8 - 0 - 9. The 9 and 0 are the wrong way round. (00:47:40)
Revealing mistake: When the team leader is opening the door to the Red Queen chamber, he clips an electronic device to the door to hack the code. The device is actually a blood glucose monitor as used by diabetics - an Accu-Chek, I think. (00:31:05)
Trivia: All the cast and crew (including the producer) had to undergo a grueling one week of military training (which they dubbed their 'week of hell') under the supervision of a battle hardened ex-navy SEAL. By the end most people were naturally eager to give their trainer a little of his own medicine. Miss Jovovich (Alice) did: he's the zombie she head kicks into the test-tube cabinet and then steals the gun from (before fighting the zombie dogs). What sweet justice.
Other mistake: Watch Milla Jojovich's hair during the scene when they are held at gunpoint by Spence. Her hair moves from shot to shot. For the most obvious, watch right after Spence shoots the zombie. (01:15:25)
Visible crew/equipment: When JD shoots the zombie female in her leg you can see the square outline of the pack behind her leg that 'explodes' and makes the hole in her pants. (00:38:10)
Continuity mistake: Near the end, when Alice, Rain and Matt are talking to the "Red Queen" in the virus lab, there is a wall-mounted LG Flatron TFT display where the Red Queen shows surveillance footage, etc. One can see an inventory type barcode label in the bottom centre of the screen. The camera cuts away briefly, and when the camera shows the display again, the barcode label is gone and the LG logo is in its place. (01:14:50)
Continuity mistake: When Alice escapes the first zombie dog and locks herself in the room, a zombie approaches her and she kicks him down. When the zombie falls you can see his tie is partially outside of his suit. When it cuts to Alice reaching for his gun, the tie is tucked inside his suit. (00:47:20)
Continuity mistake: When zombie Lisa lies dead on the floor her hair and the papers she lies on change position between the shots. (00:50:55)
Continuity mistake: The way the T-Virus capsule hits the ground is the same each time they show it, however when it's on the ground and motionless, the position is changes. During the flash back at the end that Spencer is having, the capsule is all over the place. However at the beginning, the capsule is just in a little straight pile on the floor. (00:03:15 - 01:09:30)
Other mistake: During the scene with the laser, the laser moves along the floor where the EMP device is located, several times. However, when Kaplan and Alice enter the room, the bag with the EMP unit is still intact. (00:31:15)
Continuity mistake: When the zombie dog jumps through the window Alice makes a run through the metal door and you can see the door is clean. When it cuts there is lots of blood on the door even before the zombie dog jumps on it. (00:47:45)
Continuity mistake: When the Lasers have finished killing everyone, the EMP equipment is next to the glass wall. When Alice walks over and looks in to the corridor, it's moved. (00:32:20)
Continuity mistake: In the beginning when the the cylinders are being placed in the holders, in one close-up you can see the middle cylinder being placed and that there is no cylinder to the right of it. When it cuts a cylinder has suddenly appeared. (00:02:20)
Revealing mistake: In the scene where Milla Jovovich shoots the dogs with the 9mm Beretta she obtained from the dead security guard, a closeup of the gun is shown. Watch the cycling of the slide and you will notice that the ends of the bullets are crimped, indicating the use of blanks. (00:49:55)
Deliberate mistake: When the woman is attempting to escape from the elevator, it dislodges and falls down, so then the actress is facing the ground...but when her arm hits the floor, the floor itself bends. If you watch the DVD with the commentary on, the director points out that it was a break away floor in case the actress' head accidentally snapped forward, to avoid any injury. (00:08:00)
Continuity mistake: When the person is bumped into and spills coffee on himself, the coffee stains on his shirt changes between the shots. (00:03:05)
Continuity mistake: When Matt is at Lisa's desk he looks through some papers, he is looking at a paper which has black squares on it. Then he puts the paper down and looks at another paper. When it cuts to him noticing Lisa approaching he is now holding the paper with the black squares again. (00:50:20)
Answer: Actually the T-Virus was originally meant as a cure for a genetic disorder that Dr. Ashford and James Marcus daughters suffered from. The reanimation was a side effect and James Marcus was killed by Dr. Alexander Isaacs so he could take control of it and turn it into a bio-weapon.
lionhead