The Cooper Extraction - S7-E11
Continuity mistake: When Amy says that Penny never would have met Stan Lee, she draws a thick black line between "Penny" and "Stan Lee" on the board. The camera goes to Penny, and when it comes back to Amy, the line is blue and faint.
Answer: Because Raj's selective mutism seems to be caused by women that Raj sees (on some sort of conscious or subconscious level) as a potential sexual partner. An attribute that wouldn't apply to either his sister or mother.