Continuity mistake: After Homer falls asleep at the wheel the truck starts to turn the corner. As its going around the bend you can see a white line on the road. The following shot the line has disappeared.
Continuity mistake: When Lisa finds the doorbell Marge wanted and she plays it, it is gold, but when Marge picks it up it is grey-ish.
Continuity mistake: When Red has finished the steak, he lies back and is the same position for Homer's small speech. However, as soon as Homer starts to say 'Wait, you're not breathing,' Red blinks when he is meant to be dead.
Audio problem: When the radio is playing "Wannabe", the song stops but Homer doesn't touch the radio.
Answer: I'm not sure if this is the one you're thinking of, but an episode of "Ray Bradbury Theatre," called "A Sound of Thunder," dealt with a similar matter: a group of hunters travel back in time to hunt dinosaurs, only to find things have changed when they get back because someone stepped on a butterfly.
Xofer