Revealing mistake: When the force field is activated in the Jeffries Tube, we only see the flash of light from off-screen. The effects team neglected to add the force field effect.
Continuity mistake: When commander Data is reciting the code to lock the rest of the crew out of the computer, he states the code '1-7-3-4-6-7-3-2-1-4-7-6-C-3-2-7-8-9-7-7-7-6-4-3-T-7-3-2-V-7-3-1-1-7-8-8-8-7-3-2-4-7-6-7-8-9-7-6-4-3-7-6-LOCK', but when the computer screen is shown the code reads '1-7-3-4-6-7-2-1-4-7-6-C-3-2-7-8-9-7-7-7-6-3-T-7-3-2-V-7-3-1-1-7-1-8-8-8-7-3-2-4-7-6-7-8-9-7-6-4-3-7-6-LOCK.'
Answer: He brought the Borg to the Alpha Quadrant and showed them that it was full of worlds waiting to be assimilated. Guinan's homeworld was their first stop, and they assimilated everyone and took over the planet, leaving The Survivors of her race without a home. Q is ultimately responsible for that.
Captain Defenestrator
By the time Q takes the Enterprise to meet the Borg, Guinan already knew who they were and they had already destroyed her world. Therefore the above answer can not be right. I believe Guinan is much more than she appears, and her people have had encounters with the Q in the past. It is these interactions, that obviously were not pleasant, that fuels her distrust.
oldbaldyone
That's what the above answer is saying. Q brought the Borg to the Alpha Quadrant (not Earth) and the Borg destroyed Guinan's home world in the late 2200's, which is why she hates Q. Although she met Q in 2160 and they both saw each other as enemies right away.
Bishop73