Factual error: Micaela was pushed off a cliff and landed on a ledge, and tells Zeke she has dislocated her shoulder. Zeke helps her get back to the top, and for the last push, she puts out both arms and Zeke pulls her to safety. Not possible. A person with a dislocated shoulder would not be able to move that arm.
Factual error: Escorting Saanvi and her colleague to see Dr. Cooper, NSA Agent Tim Powell flashes a gold badge and shouts "NSA" to the officers. NSA agents carry ID Badges, but not gold shields. Further, they would never identify themselves as NSA personnel to outsiders.
Answer: Only superficially. Manifest doesn't even begin with a plane crash, but rather a plane disappearing for 5 years with the assumption that it crashed, which turns out not to be true.
BaconIsMyBFF
In the particulars it seems different, but the overall plot is the same. A seemingly random group on an airplane experience a weird event and spend years trying to figure out what happened. Let's hope the reveal in the final episode is not as disappointing as "LOST" - they're actually all dead.