Continuity mistake: Right after Bennett takes off in the plane, Claire throws a gun to Alice. Between the slow-motion shots, the gun switches position in mid-air before Alice catches it. In the shot of Claire throwing it, the barrel is facing to the right, meaning that it should be facing to the left in the shot of Alice catching it. But it still faces the right when she does. (00:58:30)
Continuity mistake: When Alice is about to blow up the elevator, we get a shot of a big explosion. Anderson has been nice enough to slow this down for us, so you can see that the elevator is empty, where before there were four people. (00:59:30)
Continuity mistake: When the elevator hits the water, it starts to tilt over to one side. This contradicts the shot which shows it falling, where it fits very snugly in its shaft. (00:59:30)
Continuity mistake: Just when Alice jumps off the roof, pay close attention to the zombie directly to her right. You can see how he slows down and stops on the ledge. But in the shot directly afterwards, all of the zombies are jumping after Alice, and none are stopping where the roof ends. (01:00:10)
Continuity mistake: When Alice is shining her flashlight into the tunnel, in the far shot from the inside of the tunnel, she is leaning on a rock, on her elbows. But in the shot directly afterwards, she is still leaning on the same rock, only now on her hand. (01:01:50)
Continuity mistake: Kim Yong is killed in the shower block and his corpse falls to the floor but is never seen again. (01:02:30)
Continuity mistake: In the scene after Alice bungee's off the roof, as she runs through the crowd of zombies towards Luthor, she fires the shotgun loaded with quarters once. As she gets closer he jumps to pull the door down and as all the zombies hit the door, you can see that it's solid, no holes. But when the shot changes to the inside view, the door now has quite a few holes in it. Not only were they not there before, but the door was open, so the quarters wouldn't have hit it anyway. (01:03:50 - 01:04:20)
Continuity mistake: Alice drops her shotguns after she is knocked out by the Axeman, and a close up of the shotgun shows that it lands near one of the shower columns. And when Claire spots the shotgun, it is still lying in the spot where Alice dropped it. But in the wide shot just before Claire starts her slide, the one with both Claire and the Axeman, there aren't any more of the shower columns between them, and Claire only picks up the shotgun after the wide shot. (01:03:55)
Continuity mistake: Right after the Tower swing, Alice draws her shotguns, ready to shoot. In the close up shot of her, the shotgun in her right hand is pointing up. But in the far shot with the two zombies in front of her, it is pointing down instantly. (01:03:55)
Continuity mistake: After the Tower Swing, Alice fires a bunch of quarters through two zombies, most of which end up in the wall around Luther. But when he has closed the door, we get an overhead shot of the wall, which has a bullet hole in it - and no quarters. (01:04:15)
Continuity mistake: During the fight scene with the Axeman, Claire slides between his legs while gunning him down with Alice's shotgun. But watch his axe. In the far shot he is holding it up, like he is ready to strike, but in the shot where he is falling, the axe is leaning on the ground all of a sudden. (01:04:15)
Continuity mistake: When Alice is shining her flashlight into the tunnel, note that the shower column is on the right side of the tunnel entrance. In the shots on the outside of the tunnel, that same column is on the left side of the entrance. (01:04:30)
Continuity mistake: When Alice is knocked out by the Axeman, she lands on her back with a few broken tiles on her chest. When we get the far shot with the Axeman, there are suddenly a lot more tiles. (01:05:20)
Continuity mistake: In the flashback when Claire remembers what really happened on the beach where they landed the chopper, the Umbrella guard slams the spider-shaped device on her chest. In the next two shots, the device is gone, but when Alice finds her 18 months later, it's back on. (01:10:50)
Continuity mistake: When Alice kicks Bennett away, he lands one one of the dead bodies, sliding it back significantly. But in the shot where the dog is splitting its head, you can see the head of the body in the top right corner of the screen. And it definitely is the one Bennett landed, seeing how that was the one next to the shotguns. And in later shots, you can see that all of the bodies are in their original positions. (01:18:00)
Continuity mistake: When Bennett bends over to pick up Alice's shotgun, you can see that the floor on which it rests is covered in glass. But when K-Mart picks it up moments laters, the glass is gone. (01:20:30)
Continuity mistake: In the overhead shot with the falling glass, Alice's second shotgun is apparently lying under the table, because we can't see it. When Bennett attempts to pick it up, it has moved itself a good foot and a half away from the table. (01:24:00)
Continuity mistake: When K-Mart throws Alice's shotgun to her right before she shoots Wesker in the mouth, between the slow-motion shots, the gun switches position in mid-air before Alice catches it. K-Mart throws it with the barrel facing towards Alice but when she catches it its barrel is facing away from her. (01:24:15)
Continuity mistake: When they enter the "cargo hold" on the Arcadia and the light turns on, the camera shows the room is empty and completely white. When Alice reaches the other end a few min later there is a blood trail along the floor into another room.
Continuity mistake: During the scene on the rooftop, after shooting some approaching zombies, the group run into the lift while shooting a bunch more zombies. The bomb then explodes, sending the lift down. The scene goes back to Alice fastening herself on a sling. When the camera moves to show the zombies, all of the zombies have moved back some 25 feet away and all of them are standing still, waiting patiently for Alice to make the next move. Alice turns around to run to the edge of the building, and we can see that the zombies who had been shot earlier and should still be lying around have magically disappeared.