Factual error: When Tommy and Kathy go to visit the madame, that part of the movie is set in 1994, but we see two cars that don't fit in that year: a gray 1997-2004 Volkswagen Passat that drives past, and a gray 1996-1999 Citroen Saxo parked a few meters away from madame's house. (01:21:20)
Continuity mistake: When Travis is attacked by Barris at the end of the experiment, he "catches" the knife and his hand is seriously injured, becoming covered in blood. However, when the red light begins to go off and Travis raises his hands to his head, both of them are clean and uninjured. (01:25:25 - 01:26:45)
Continuity mistake: In the first shot of the dead man hanging form the tree, his head appears to be about 12" from the tree limb. After Mattie climbs up to cut him down, his head is several feet from the tree limb.
Continuity mistake: When Aron Ralston falls off the bike he is thrown few yards away of his bike into a bush. However, when he is taking the photo the bike is under his head.
Continuity mistake: When Nina and Leroy are standing halfway up the stairs as he is about to announce that she is the new star ballerina, they both hold a glass of champagne. At first, Nina's glass is almost empty; at the end of the scene however, she is holding a full glass.
Continuity mistake: When Ally comes home and fights with her father after getting drunk and staying out all night, the strap of her white top is hanging down at her shoulder, but as the shot changes it moves up on her shoulder without Ally moving it. This changes constantly throughout the scene.
Continuity mistake: While eating in the mess hall in India, the Girl was wearing glasses but in the wide angle back view, the eyeglasses were on her forehead. (01:01:40)
Factual error: At the start of the movie it said "NEW YORK CITY 2000", then went to a panoramic view of New York City minus the Twin Towers. Even though they stated the year was 2000 and they didn't go down until 2001.
Factual error: As the three Israeli agents are stepping off a plane in Israel in 1966, one of the cars viewed behind them is a 1978 Olds 98 (with its late 70's square headlights). (00:01:45)
Other mistake: In the scene where Jensen is attempting to decrypt the password on the hard drive with the algorithm, he uses the command "traceroute d-hea" which is commonly used to test network connectivity, not decrypt passwords.Then follows it with the command "dir" to reveal HTML code instead of directory structures.
Factual error: In the home video scenes, which were supposed to have been filmed during the 1970s or earlier, young Mickey Ward is shown wearing gloves bearing the Title Boxing logo. The Title Boxing company wasn't founded until 1998.
Plot hole: Modern diabetes management will tell a patient immediately if their glucose levels are out of the ordinary. Results are not monitored and delivered to a county jail by an outside lab. If a diabetic is sick enough, they would have obvious physical indications. The entire escape plan hinges upon these fallacies.
Continuity mistake: Before Lisa goes to Matty's house, he swaps from standing side by side to the doorman, to a meter behind.
Visible crew/equipment: Near the end of the movie while Will Ferrel is going to the bathroom in his house, the camera person is visible in the mirror off to the right of the screen.
Factual error: The movie starts off saying its 2007 and Smart Cars were not sold in the US until 2008.
Plot hole: When Andromeda and Perseus wake up on the beach, Andromeda tells Perseus that Argos needs a new leader/king. The problem with this is there is nothing onscreen to show that she even knew her father the King had died. She was hanging by her arms facing the Kraken and she couldn't turn around. By the time her father died, she was already falling into the sea, so again, she shouldn't even know her father has died.
Factual error: Clooney refers to the rifle as an "M14". The Rüger Mini-14 is a different rifle than the M14 (used e.g. by the Marine Corps prior to the M16).
Continuity mistake: When Lynch climbs out of the ski chair the second time, there is a shot looking up, and the chair where Parker should be is empty.
Visible crew/equipment: In almost every scene with Stanley Tucci, you can see stage lights, crew members, or other equipment reflected in his eyeglasses.