Trivia: During a speech in Toronto, Bradley Cooper told audiences that people in Las Vegas didn't even notice they were filming a movie, even though he had bloody tiger scratches on his neck, and Justin Bartha was beet red, nobody stopped to look.
Trivia: When Carl's house begins to lift and the little girl looks out her window, the Luxo ball from Pixar's other films is seen in her room.
Trivia: Ewan McGregor asking "What is a Jedi Knight?" is especially ironic (and probably an "in joke") because he famously played Jedi Knight Obi-Wan Kenobi in the Star Wars prequel films.
Trivia: Kevin James's real-life wife, Steffiana De La Cruz, plays "the lady with the kids in the mall." She takes a lingering glance as he rolls away on his Segway.
Trivia: Ike Eisenmann and Kim Richards, who played Tony and Tina in the original Escape to Witch Mountain, make cameos as a sheriff and waitress, respectively.
Trivia: The guy at the gas station is also the guy that gets eaten by a zombie whilst on the toliet at the start of the film.
Trivia: When Andy and Bruce are back home after Dave asks if Andy can come to the party, Andy says she wishes that Bruce can make her a dress. She says that Bruce is a wizard, which is more than a coincidence, since Jake T. Austin also plays main in "Wizards of Waverly Place".
Trivia: The girl dancing next to Miley's grandmother in the Hoedown Throwdown scene is Miley Cyrus's real-life sister, Noah Lindsey.
Trivia: When Wong drains Flamingo Lake to water his golf course and the flamingos are sucked down the plughole, in amongst their startled squawks you can hear one yelling "SH*T!". Listen for it - it's very clear.
Trivia: Mason is portrayed by actor Ken Kirzinger who played Jason Voorhees in 2003's Freddy vs. Jason. Mason is a parodied version of Jason.
Trivia: Isla Fisher (who plays Rebecca Bloomwood) admits that she actually hates shopping.
Trivia: In Paul Rust's bedroom, his picture of Hayden Panettiere on the ceiling is from her movie "Bring It On: All or Nothing." She was a cheerleader and the colors are those from her school in the movie, Crenshaw Heights. And yes, they say in the high school gym during the cheer that the school's colors are yellow and blue, but that is where the picture is from.
Trivia: When the main group decides to reconstruct the Bible, they flip through the library cards of the those who have used it. The first name on the first card is Noah Levenstein, who they subsequently call. One other card is visible next to it; the first name on that list is Kevin Myers, the guy who was given the Bible in the first American Pie movie. (01:04:15)
Trivia: Christa B. Allen, who plays the teenaged Jenny, had previously portrayed another younger version of a Jennifer Garner character in 13 Going On 30.
Trivia: At 1:29:19 actress Jane Seymour is seen wearing a necklace from her Open Hearts jewelery collection.