Selling Out - S1-E9
Frasier: Roger, at Cornell University they have an incredible piece of scientific equipment known as the Tunneling Electron Microscope. Now, this microscope is so powerful that by firing electrons you can actually see images of the atom, the infinitesimally minute building blocks of our universe. Roger, if I were using that microscope right now, I still wouldn't be able to locate my interest in your problem.
The Post-Modern Prometheus - S5-E5
[After spilling coffee on his lap.]
Mulder: Great, now my crotch will be up all night.
Niles: You know, the next time you give your clothes away, why don't you just stay in them?
The Way of the Warrior (1) - S4-E1
Julian Bashir: They broke seven of your transverse ribs and fractured your clavicle!
Elim Garak: Ah, but I got off several cutting remarks which no doubt did serious damage to their egos.
A.D.A. Alex Cahill: How about a cruise for our honeymoon?
Ranger Cordell Walker: We've already done that.
A.D.A. Alex Cahill: That was a river raft.
Ranger Cordell Walker: Close enough.
Lord Bowler: Uh oh. You hit the sheriff.
Brisco County Jr.: Yeah, but I did not hit the deputy.
Penhaligon: To be left at the airport, Fitz, that's one thing. But to be left by a big, fat, egocentric, middle-aged man, well, that's a different thing altogether.
Fitz: I didn't mind the big.