Continuity mistake: When Derek is explaining to his patient about the risks of the brain surgery operation, Derek's hands move from his coat pockets to up near his chest, and back to his pockets. (00:30:40)
Continuity mistake: Izzy tells the male patient she is a good doctor even though she was a model. Her hair is parted to the left and in the next shot it is parted to the right.
The Self Destruct Button - S1-E7
Continuity mistake: At the beginning of the episode, Izzy takes a purple plastic cup of coffee with her to work. In the parking lot she now has a coffee in a disposable paper cup. Then in the locker room, she is back to having the purple plastic cup of coffee. (00:02:25)
The Self Destruct Button - S1-E7
Continuity mistake: When Izzy, George and Christina walk over to the vendor, talking about Dr. Sheppard and Meredith, Izzy is in the middle, eating snacks from a packet. Between shots she alternates from holding the pack either up or down. (00:23:00)
The Self Destruct Button - S1-E7
Continuity mistake: While Meredith and Izzie are in the kitchen discussing Derek, Izzie sets the freshly frosted whole chocolate cake on the counter, but when she takes a seat in the closeup there's a slice of cake already on the plate, and in following closeups the cake is either whole again or back with the cut slice. (00:39:45)
Continuity mistake: When everyone sits down for lunch, Izzy's bottle of water jumps from her tray to in her hand (as she drinks) between shots. (00:17:20)
Continuity mistake: Meredith takes over injecting George for Alex, and right after she stands behind George, Alex leaves. Just when he opens the door, suddenly you can see Alex is behind George and Meredith is just coming in again. (00:19:55 - 00:20:50)
Continuity mistake: When Meredith is trying to give George the shot of Penicillin the gloves on her hands suddenly appear in one shot. (00:20:00)
Continuity mistake: When Addison shows up at the end of the episode, the umbrella she holds keeps changing position and swapping hands between shots. (00:42:05)
Continuity mistake: When Addison introduces herself to Meredith, she reaches out to shake Meredith's hand twice.
Enough Is Enough (No More Tears) - S2-E2
Continuity mistake: When George kisses Olivia's forehead as he 'dumps' her, he embraces her head with his hands, but in the next closeup his hands aren't on her head. (00:38:55)
Continuity mistake: When Meredith and Christina lay on the grass in the park, Meredith's hands are on her chest but are by her sides in the next closeup. (00:01:55)
Continuity mistake: When Derek and Richard are in the lift talking, you can see Richard's head bandages under his hat. But when he removes his hat, his head is bare. (00:03:20)
Continuity mistake: When Derek and Addison are examining the premature baby and then begin to argue, Addison's elbow is resting on the glass case in some shots, but is instantly down in others. (00:09:30)
Continuity mistake: When Ellis Grey is shouting at George, calling him Thatch, Alex and Meredith run to the open door of her room. But in some shots you can see they are no longer in the doorway but are then suddenly back again. (00:16:55)
Continuity mistake: When George askes Richard Webber if he could help examine Ellis Grey, the extras in the background walk down twice and suddenly appear and vanish. (00:18:10)
Continuity mistake: When everyone rushes Christina out of the OR after she collapses, Izzy suddenly loses her blue scrubs hat between shots, with no time to remove it herself. (00:23:50)
Suggested correction: She did have the time to change. And you can see in the end of the scene when Bailey is talking to her in the elevator and Izzie is outside, the mask and the hat in her hand.
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Continuity mistake: We see a nurse writing down "Yang, C" on the assignments board; note the handwriting. Later, when Burke notices that Christina's name is on the board, the handwriting of "Yang, C" is completely different and other minor writing differences are noticeable too. (00:27:55 - 00:33:45)
Continuity mistake: As Meredith tries to get in to see Christina, but Bailey walks over to stop her, Meredith is putting on a white surgical mask. In the frontal shot she ties the white straps of the mask into bows. But in the next shot from behind the straps hang loose and aren't in bows. (00:29:50)
Continuity mistake: When Meredith tries to get into the OR to see Cristina, Bailey walks over to the door to stop her, and they talk. But in the final shot of Christina, you can see Bailey's hands on her head, even though Bailey is at the door with Meredith. (00:30:00)