Plot hole: Rex is in the hospital for having a minor heart attack and is awaiting surgery to receive a pacemaker. 1) He isn't connected to an ECG or any other heart monitor so no one is aware of his heart attack. 2) They ran blood tests and checked his potassium levels. They would have also checked the concentration of his medication in his blood. (This should have been done earlier in the season too when they first discovered his medications were not working.) Zero concentration of medication in his blood could throw suspicions on his wife just as easily intentionally giving him potassium.
Desperate Housewives (2004)
1 plot hole in One Wonderful Day
Look Into Their Eyes and You See What They Know - S5-E19
Other mistake: In an earlier episode where Edie and Susan are driving Martha Huber's ashes to the lake to be spread, Edie gets a flat tire and Susan changes it. In this episode, all the girls are driving with Edie's ashes and they get a flat tire. Susan asks "Does anyone know how to change a flat tire?" Did she forget how?
Bree Van De Kamp: It's the age-old question, isn't it? How much do we really want to know about our neighbours?
Trivia: Across Season 4: Two Lois Lanes appear together in this season: Teri Hatcher played Lois Lane in The Adventures of Lois and Clark and Dana Delaney voiced Lois Lane in Superman: The Animated Series and its follow-ups.
Question: When the housewives first met, what card game did they play?
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Chosen answer: Poker. They have been playing that this whole time, once a week with everyone who was invited that lived on the Lane.