Plot hole: Rex is in the hospital for having a minor heart attack and is awaiting surgery to receive a pacemaker. 1) He isn't connected to an ECG or any other heart monitor so no one is aware of his heart attack. 2) They ran blood tests and checked his potassium levels. They would have also checked the concentration of his medication in his blood. (This should have been done earlier in the season too when they first discovered his medications were not working.) Zero concentration of medication in his blood could throw suspicions on his wife just as easily intentionally giving him potassium.

Desperate Housewives (2004)
1 plot hole in One Wonderful Day
Other mistake: Throughout the sixth season Eddie Orlofsky attends school with Porter Scavo, and Danny Bolen, witch means they must be close in age. However, in season 6 episode 20, it is revealed that Eddie was in high school the same time as Danielle. This does not make sense due to the fact that while Danielle was in high school, Porter and Preston were about 10.
Bree Van De Kamp: It's the age-old question, isn't it? How much do we really want to know about our neighbours?
Trivia: Teri Hatcher (Susan), Felicity Huffman (Lynette) and Eva Longoria (Gabrielle) are the only cast members to appear in every single episode of the series.
Question: When the housewives first met, what card game did they play?
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Chosen answer: Poker. They have been playing that this whole time, once a week with everyone who was invited that lived on the Lane.