Continuity mistake: Season 5-24, Episode: My Transition (1). The first time we see J.D. and the flyer about his deck, the flyer has a picture of J.D. looking straight ahead smiling and the writing on it reads "Old? Gay? Like Decks?" After J.D. rips the flyer off and shows it to the janitor, the picture of J.D. has changed to him giving a thumbs up and the writing has also changed to "Come and Chill at my big gay deck."
Scrubs (2001)
22 continuity mistakes in season 5 - chronological order
Starring: John C. McGinley, Zach Braff, Donald Faison, Neil Flynn, Sarah Chalke, Ken Jenkins, Judy Reyes
My Way Home - S5-E7
Character mistake: Early in the episode, Keith pages JD from home to the hospital. When JD arrives, he asks Keith what's the big emergency and Keith asks if he wants the patient to be prescribed unfractionated or low molecular weight heparin. JD gets angry and says that they're the exact same thing. This is in fact completely incorrect. Low molecular weight heparin is made from fragments of unfractionated heparin. They have different effects in their metabolism, half life and dose monitoring (unfractionated needs a blood test, low molecular weight doesn't). The choice between unfractionated and LMWH is an important clinical decision and should not be dismissed as "the exact same thing".
My Unicorn - S4-E11
Dr. Cox: I love this moment so much I want to have sex with it.
Trivia: The picture of the lady in Ted's office is his real-life mother.
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Answer: Dan was drinking beer and Cox feared that Dan might get so intoxicated he would fall asleep and drown in the tub.
Mortug