Other mistake: When everyone is eating the boar at the end, the boar is completely intact, yet everyone except for Lisa is seen with a piece of it. (00:20:30)
Revealing mistake: When Skinner talks to Otto on the bus, the point of his hair is touching a pole. Look at the pole - Skinner's hair is going through it.
Continuity mistake: Whilst everyone is eating the boar, they are noticeably moving. But when it cuts the final wide shot, no-one is moving an inch.
Continuity mistake: When everyone discovers the monster is a boar, there is a Chippos packet on its tusk. But when the boar is shown licking the slime, the Chippos packet has disappeared without ever being touched.
Continuity mistake: When Milhouse swings across the vine, he lands on the ground and the vine isn't on the ground. Two shots later, the vine is suddenly on the ground.
Continuity mistake: Whilst running away from the others, Milhouse runs out of breath and falls over. In the shot where he is lands on the ground he has sweat on his face, but in the previous shot, no sweat was visible.
Other mistake: When Bart, Lisa and Milhouse run away from the others, Lisa steps right on a puddle but no splash or ripple is made.
Continuity mistake: Just before Homer meets Bill Gates, and during the meeting, the pens and pencils in the butter alternate between shots.
Continuity mistake: When Bart, Lisa and Milhouse first run away from the others and Nelson puts his fingers in the ash from the fire the night earlier, the twigs that remain in the fire disappear almost instantly.
Continuity mistake: Throughout the trial, the twins keep switching places between shots. Note - one twin has a bow in her hair and the other twin doesn't.
Continuity mistake: When Bart says "No talking in the cage", both him and Milhouse are right next to each other. But two shots after Lisa says Milhouse is the only witness, Milhouse is a good 10 foot away from Bart without ever having moved the cage he was in.
Continuity mistake: At the start of the trial, Nelson is seen sitting in front of Martin and one of the twins. But in the shot after Lisa says Milhouse is the only witness, there is no sign of Nelson.
Continuity mistake: When everyone discovers Milhouse has eaten the food, Milhouse then says "You wouldn't dare hurt me. You forget, I have the glasses." After this line, Nelson takes off Milhouse's glasses. At this point, a rip is visible on the left side of Nelson's shirt. Milhouse then walks backwards and Nelson is seen re-entering the shot from behind Milhouse. Only now, the rip in Nelson's shirt is now suddenly on the right side of his shirt.
Continuity mistake: When everyone sees Milhouse after they find out the food has disappeared, Milhouse's arms are by his head. In the next shot, one of his arms is suddenly on his belly.
Continuity mistake: When everyone notices no food in the cooler, the cooler lid is raised, then it is down, then it is suddenly raised.
Continuity mistake: When everyone takes food out of the cooler, Bart has a bag of OREOs which magically becomes a bag of different cookies.
Continuity mistake: When the kids wash up on the island after the bus falls into the ocean, we can see they are totally dry. But they were just in water a minute ago, so they should be soaking wet.
Audio problem: When Milhouse is saying he's getting swimmer's ear, his mouth is out of sync whilst saying it.
Audio problem: When the bus is flying off the bridge and Otto says "Which way should I turn?" look closely at him when we can see his face during the line. We can see his mouth is out of sync when he's saying it.
Answer: I'm not sure if this is the one you're thinking of, but an episode of "Ray Bradbury Theatre," called "A Sound of Thunder," dealt with a similar matter: a group of hunters travel back in time to hunt dinosaurs, only to find things have changed when they get back because someone stepped on a butterfly.
Xofer