Continuity mistake: At Moe's, when Homer takes hold of the telephone its color is red, but then changes to blue as he speaks to Marge. (00:02:30)
Continuity mistake: The old men beside Grandpa when Homer plows the retirement home switch places, depending on whether it's a long or a close shot. (00:10:00)
Continuity mistake: When Bart arrives at school in the bus, after Homer plowed the road for the bus, the sidewalk is covered in snow except for Martin's footprints. Then, when he gets out, the sidewalk has been shovelled, as there is no snow on it. Following this, Bart is pelted by snowballs, which sends him falling face-first into the sidewalk, which is once again covered in snow. (00:10:20)
Continuity mistake: When Homer hands over the key to Mayor Quimbey, the mayor points out the teeth marks on it. But in the next shot when Homer says he thought there was chocolate inside, the bite marks are gone. (00:16:30)
Answer: I'm not sure if this is the one you're thinking of, but an episode of "Ray Bradbury Theatre," called "A Sound of Thunder," dealt with a similar matter: a group of hunters travel back in time to hunt dinosaurs, only to find things have changed when they get back because someone stepped on a butterfly.
Xofer