Continuity mistake: Tom is sitting on Frasier's couch and has one hand on the arm of the couch and one on his knee. In the next shot he has both hands in front of him. (00:12:15)
Continuity mistake: Near the beginning of the show, Daphne is having a smoke, and Frasier takes it from her - her hand is on her knee but when the shot changes it is in her lap.
Continuity mistake: Niles goes to Frasier's apartment and meets Tom, the new station manager. Niles is talking to him with his hands clasped in front of him but in the next shot his hand are clasped behind his back.
Answer: Nanny G (Nanette Guzman - played by Laurie Metcaf) has been a children's entertainer for twenty years, and tells Frasier, "Do you know what it's like to play the same character for 20 years?!" The joke is that Kelsey Grammer has been playing Frasier Crane since 1984, when the character first appeared on "Cheers", so Kelsey in real life has been doing just that!
Super Grover ★