Character mistake: Early in the film in the scene in which Precious is in math class just before being called to talk to the principal, on the blackboard someone, presumably the teacher, has written REQUIRMENT, which is a misspelling of "requirement"
Character mistake: While Precious is in the hospital, her teacher is writing a response to Precious' journal entry in which Precious had written about her grandmother having referred to her as a "dog." In the note the teacher wrote, it says "Dear Precious, You are not a dog. You are a wonderful young women." instead of "You are a wonderful young WOMAN."