Continuity mistake: In the opening scene, the pages change in the magazine that the convenience store clerk is reading. (00:01:30)
Continuity mistake: In the liquor store, Seth kicks a shelf to get lighter fluid. Look closely - it is an overhead kick which means that his foot would be upside down. However Seth's foot is the right way round. (00:07:45)
Continuity mistake: At the motel, as Seth and the owner are talking, the owner is hunched over. It cuts to his face and he is standing erect. (00:11:50)
Continuity mistake: When Seth introduces Gloria to Mr. .44, the gun is level and pointed at the door. Cut to over Seth's shoulder and the gun is pointed at the ceiling. (00:14:55)
Continuity mistake: After Seth and Richie capture the Fullers, Seth sends Richie outside to start the car. Richie picks up the keys, stands up facing Kate, then exits past her to the right. As the door closes, she is standing against the wall - he would have walked to the left to pass her. (00:29:00)
Continuity mistake: Right after the Geckos capture the Fullers and are driving off, Seth is talking to Jacob in the front seat. The light and shadow on Jacob's hat change between shots on his face and shots on Seth. (00:32:00)
Continuity mistake: At one point the RV is going down a rough, bumpy road and inside Seth and Richie are talking and everything is perfectly still. (00:42:30)
Continuity mistake: As Santanico Pandemonium begins her dance, she tosses her cloak off and a stage hand emerges to remove it almost immediately. The stage hand then disappears in two shots of Santanico onstage, then reappears folding the cloak. (00:55:00)
Continuity mistake: As Santanico begins her dance, she swirls her cape. On the third "swirl" a snake appears. The camera shot goes to behind her and the snake's head is working its way up her back. Then in the next shot, the snake's head is round the front and works its way upwards towards her head. (00:55:20)
Continuity mistake: During Santanico Pandemonium's routine, two dancers take the snake away so she can step forward. As they take the snake off, the second dancer is holding only a couple feet of the snake's tail, but in the next shot, the second dancer is holding the entire snake. (00:55:40)
Continuity mistake: When Richie stabs the bartender, the blood on the knife is green, however, throughout the rest of the movie, all the other vampires have red normal blood in them. (01:00:35)
Suggested correction: Not true. When Kate shoots Scott when he's being attacked by the vampires and they explode, you can see green blood dropping to the floor.
Continuity mistake: When Sex Machine turns into a vampire, he covers his mouth so he doesn't show his fangs. When his hand changes, he tries to cover it up with his other hand. Watch this other hand. In the shot where THAT hand changes, it is in a different position from before. (01:21:35)
Continuity mistake: While Seth is talking to Carlos about the loss of his brother and Kate's family, Kate turns around to survey the damage. Two quick cuts later and she's facing exactly as she was before, down to the facial expression. (01:38:15)
Continuity mistake: Throughout the entire film the tattoo on George Clooney's neck moves position and changes shape.
Continuity mistake: In the final battle, Jacob turns into a vampire and bites Scott, when Scott hits Jacob with the holy water bomb, Jacob backs away from Scott, when Jacob removes his mouth from Scott's neck, there is no blood on it, two cuts later, there is blood on Scott's neck.
Continuity mistake: When Jacob gets bitten, he is thrown across the room by Sex Machine. If you look closely as he's flying through the air, you can see the wound on his arm has disappeared.
Continuity mistake: In the shot where we see the bar (for the very first time) they are going to, you can see the background is flat, kind of like the building is on a flat area of land with nothing behind it. At the end of the film we see not only a giant ditch but also the trucks from over the years piled up behind the bar.
Continuity mistake: During the scene when Seth questions why the bartender will not serve him, several camera shots go to the band on stage You don't even have to watch carefully to know the band, especially the drummer, are not playing their instruments and/or their miming is way off.
Continuity mistake: In the hotel when the manager comes through the door, in the first shot the door is open, but the next time the door is closed.
Continuity mistake: Frost gets green blood all over his hand after holding the vampires heart, but this disappears while they are fighting the four women. After the fight finishes, the blood returns.