Continuity mistake: The breast pockets on Betty Ross's denim jacket switch from buttoned to unbuttoned between shots when she is confronted by David Banner in her house at night, and again, later, when she approaches the Hulk in downtown San Francisco.
Continuity mistake: When the Hulk is standing in the street, we see him standing in the fountaining water from the smashed hydrant but his hair never gets more than damp.
Continuity mistake: When Bruce first arrives at the lab in the beginning of the movie, Betty tells them that they have to present to the review board on Tuesday. After the experiment where the frog explodes Bruce asks Betty what should they present for Monday.
Continuity mistake: When the dad of the hulk comes to see his son for the "deal" he made to turn himself in to the military. You can see the type of handcuff the dads wearing changes kind two or three times in the scene.
Factual error: The jet aircraft that the Hulk hangs onto couldn't have flown as high as it's shown to. The max altitude of the F-22 is currently 50,000 feet, any higher than that and the pilot would have to wear a specialised flight suit. To see 'space', an aircraft must reach a height of 90,000 feet, which is almost double the 'safe' altitude for pilots, not to mention the F-22 lacks the engines of the SR-71 or U-2 to cope with the low oxygen levels of the upper atmosphere.
Factual error: In the scene where General Ross is calling in the desert with a satellite telephone, he is using a Thuraya satellite phone. These phones only have coverage in Europe and a large part of North Africa. Since he is using the phone in the US, the phone shouldn't work there.
Deliberate mistake: When Hulk meets his father at the lab, each one's eyes have a special light on them. This adds for dramatic effect, but it's absurd because there is no direct source of light since each one is in front of the other and their faces are in shade in the rest of the shots.
Factual error: In the scene where they're in the lab and on the computer screen they show a strand of DNA you see cc matched up many times. If they knew anything about biology they would have matched C (cytosine) with G (guanine) which is the proper way in which DNA replicates.
Audio problem: During the scene where Talbot approaches Betty by the elevator, it splits and in doing so the top left screen does not speak, but the bottom right does, and they are supposedly "Sync"ed.
Audio problem: During the scene where Bruce's father is giving him the green dinosaur toy and the monkey toy and suggests making them have a fight, the boy "Roars" but his lips don't move at all, in fact his mouth is shut.
Factual error: In the scene in the desert, when the Hulk picks up the tank by the turret, the hull of the tank stays attached. The turret actually isn't attached to the base, it sits on a rotator ring and is held in place by gravity. (Turret weighs about 25 tons, if I recall).
Continuity mistake: When Betty is talking to Bruce about accepting their breakup, the camera from the front shows her looking right at him, but the camera from the back shows her looking down.
Continuity mistake: Betty is touching the door panel to scan her identification but in the next shot she has not reached the door yet.
Factual error: When the Hulk is jumping from mountain tops to mountain tops, it is amazing at which speed he falls back on the next mountain. There is nothing wrong with him jumping very quickly at a 20,000 foot altitude (because he is very strong), BUT, the Hulk should not go down faster than a free falling object. Unless he has superman powers, falling from the top of his trajectory to the next mountain top should take something like 2-3 minutes. In other word he should not fall faster than the average skydiver.
Suggested correction: He is shown jumping 150-200 feet high, not 20,000ft.
Factual error: In the final duel between the Hulk and his energy-absorbing father in the remote lake, an aerial military task force drops a tactical nuclear missile on the lake, effectively sub-atomizing the Hulk's dad in an instant. While acknowledging that, yes, the Hulk himself might even survive a nuclear detonation, there is no doubt that the small lake (as well as Hulk's one-size-fits-all purple pants) should have been completely vaporized at temperatures of tens of thousands of degrees. However, immediately after the blast, we see the normal Bruce Banner drifting peacefully in the lake (which is not boiling nor even steaming) with his form-fitting purple pants entirely intact.
Factual error: In every scene that Gen. Ross is wearing his service dress uniform, the Armed Forces Expeditionary Medal (second to bottom row, viewer's left) is upside-down. The three center stripes should be (from viewer's left to right) blue, white, red; not red, white, blue.
Other mistake: In the scene in the underground base, where the Hulk is destroying the area, when the General orders them to turn out the lights and show him the way out, the keyboard that she grabs to type in the commands is not plugged in. Right as she grabs the keyboard, you can see the plug laying on the floor beside it.
Continuity mistake: In the scene where Nick Nolte is in Bruce's lab, after he exposes himself to gamma rays his hair is almost completely black, but in the rest of the movie it is greyish-brown.
Continuity mistake: In the pic with Betty there is no sun on it, but in the flashback the sun is shining on the tree.