Revealing mistake: When Julia takes the cigarette from the doctor in the room with the mirror, you can see, if you look closely, that there is no blood on the cigarette. But, the hand she has the cigarette in left some blood on the hand of the doctor. (00:36:10)
Continuity mistake: When Browning lies down while cutting himself, the mattress under him is dry and his blood is only smeared over his chest. Yet when the shot cuts to Channard and back, the mattress has suddenly become utterly soaked in Browning's blood. (00:30:00)
Visible crew/equipment: When Tiffany almost falls off of the ledge, you can briefly see a wire on her back.
Continuity mistake: When Dr. Channard is being turned into a Cenobite, his tie disappears in some shots. (01:04:45)
Revealing mistake: When Julia first emerges from the mattress and is scrabbling on the floor, you can see the body double is actually wearing a thong. (00:30:35)
Suggested correction: That's actually just groin/buttocks muscle and tissue. If you compare it to medical images, while some features are exaggerated, it matches up reasonably well. The fat/muscle/tissue does almost form a thong-like shape in that area. Furthermore, what purpose would there be to having the actress wear a thong when she's already covered in head-to-toe prosthetics that hide everything? That makes no sense.
Continuity mistake: When Tiffany goes back to retrieve the diamond shaped box from Julia's grasp, the position of Julia's fingers around the box change between shots, as Tiffany reaches down to grab it out of her hand.