Trivia: Jennifer Connelly voices the "suit lady", the AI in Spider-Man's suit. In real life she's married to Paul Bettany, who voiced Jarvis, the AI in Iron Man's suit, and who later played Vision.
Trivia: When Spidey sits on a lamp post, behind him on a wall there is graffiti with the name "Bagley" on it - that's a reference to the Ultimate Spider-Man artist Mark Bagley.
Trivia: Principal Morita of the school is a descendent of Jim Morita, seen in action in Captain America: The First Avenger. He also has a photo of him in his office.
Trivia: Longtime actor Michael Keaton seems permanently attached to winged superhero roles. Keaton began the superhero phase of his career in 1989 as "Batman" in the original film and its first sequel. Keaton was nominated for an Academy Award for 2014's "Birdman," playing a washed-up actor who was once a flying superhero movie star. In "Spiderman: Homecoming," Keaton plays the high-flying villain Adrian Toomes (aka "Vulture").
Trivia: Tony Revolori received death threats after he was cast in the role of Flash Thompson.
Trivia: Michelle has the same personality as Gwen Stacy from Marvel's Ultimate Universe.
Trivia: Adrian Toomes is never referred to as "The Vulture" in the movie.
Suggested correction: Not exactly true. After Spider-Man defeats Toomes at Coney Island and leaves him tied up for the authorities, the note he leaves that Happy reads refers to him as the "Flying Vulture Guy."
Trivia: The gauntlets used by the shocker are an upgrade of those used by Crossbones in Captain America: Civil War.
Trivia: The license plate on Shocker's van is MAR4667, that's a reference to Amazing Spider-Man #46 from March 1967 which was his first appearance.
Trivia: There is a post credit scene with Captain America.
Trivia: The scene where Peter is trapped under the rubble of Vulture's lair and uses his spider strength to lift the concrete off himself and escape is a recreation of a famous scene from Amazing Spider-Man #33.
Trivia: John Leguizamo was nearly cast as the Vulture before Michael Keaton finally accepted the role after multiple offers. Leguizamo stated on his Instagram account that the studio just used him as a pawn to get Keaton to accept the role, and that he could have sued if he wanted.