Continuity mistake: It was briefly stated in the second film that the T-Virus was created by Dr. Ashford to cure his daughter Angela and that the Red and White Queens were based on her. This movie contradicts that by suggesting that Dr. Marcus created the T-Virus to cure his daughter Alicia, and that the Red/White Queens were modeled after her. While the rest of the movie stays true to the continuity of the previous films, this rather obvious ret-con is still a major continuity gaff.
Resident Evil: The Final Chapter (2016)
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Directed by: Paul W.S. Anderson
Starring: Milla Jovovich, Ali Larter, Ruby Rose, Iain Glen, Shawn Roberts
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More mistakes in Resident Evil: The Final Chapter
Dr. Isaacs: We've played a long game, you and me, but now it's over.
Alice: Yes. Yes, it is.
Dr. Isaacs: I made you.
Alice: Yeah. Big mistake.
Trivia: The film's production was quite troubled. A crewmember named Ricardo Cornelius was killed in a freak accident when he was crushed by a Humvee and a stuntwoman named Olivia Jackson was severely injured, with her face being "de-gloved" and sustaining may injuries and fractures which resulted in the loss of her right arm. Thankfully she survived and made a full recovery and the doctors were able to surgically mend her face and other injuries.
Question: In Resident Evil Extinction, the White Queen says Alice's blood is the cure for the whole infection. So what the heck was everyone doing the whole time? Why act so surprised to find a cure, which by the way came out of nowhere, when you were the cure the entire time?
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Answer: In all honestly... this film series isn't one to shy away from ret-conning elements of prior films. ("Ret-con" being short for "retroactive continuity" - a storytelling device in which rules and plot-points are either changed or ignored in later installments.) This just seems to be another example of a ret-con. The idea that Alice was the "cure" all along would have ended the series a lot sooner, and they wanted to make more movies, so they just sort-of "ignored" this idea in the sequels that followed "Extinction."
TedStixon