Trivia: Vinnie Jones claimed he was offered a cameo role in this film reprising his role as Juggernaut from X-Men: The Last Stand, but turned it down as he did not like the process of having his costume put on.
Trivia: This film's trailer was infamous for a line of dialogue (that didn't appear in the actual film) in which Cassie woodenly says, "He was in the Amazon with my mom when she was researching spiders, right before she died." John Mulaney sarcastically compared the line at the 2024 Oscars ceremony to memorable quotes from Jaws and When Harry Met Sally.
Trivia: When the Xenomorph lands over Kay, director Fede Alvarez asked for a bucket of cold water to be thrown at Isabela Merced to obtain a better scare face. Isabela says she was not informed earlier that they were going to throw cold water on her, so the face you see in that scene is her real face of fright trying to catch air because of how scared she was.
Trivia: This is the first MCU film since 2008's The Incredible Hulk to feature Liv Tyler as Betty Ross and Tim Blake Nelson as Samuel Sterns a.k.a. The Leader. They were the last two of that film's five main characters to reappear in the franchise.
