Continuity mistake: After Ali has thrown his chain at the PM and is heading back to Ricky and Dave, he bends to pick it up. In the next shot of the PM, you can still see the chain.
Continuity mistake: During the scene in which the homeless character portrayed by Steve Buscemi is having a conversation with Longfellow, he is eating a slice of his favourite pizza; French Fries & Oreos. In shot in the scene Buscemi takes a bite out of the slice of pizza, and there is one Oreo on the slice, toward the front of it. Then the shot goes to Longfellow for a moment, and in the next shot of Buscemi, the Oreo is suddenly at the other end of the slice. The Oreo continues moving from the front to the back of the slice throughout the scene. (00:11:25)
Factual error: When the archangels jump from the helicopter, the "bait" is looking behind him saying he can see the dragon. For a parajumper to look between his legs to view behind himself, he would de-arch and thus de-stabilise himself while travelling at that speed. It would send the jumper into a barrel-roll spin.
Continuity mistake: The speech that Moore claims/shows then NRA president Charlton Heston giving in Colorado is actually several speeches edited into one. Note how Heston's clothing changes between cuts during this speech.
Other mistake: When the Pirates are arrested in Nineveh, another soldier walks up to Jonah and knocks him out with a fish. When this happens, Jonah is wearing the Cheese Curl hat. When he comes to on the Slap of No Return, he is wearing his turban again. Would the soldiers change his hat?
Revealing mistake: When Chosen One meets Ling and she shows her bra for a second, her shirt doesn't even open the way she opened it. (00:17:40)
Continuity mistake: When Shawn is teaching the new drummers not to look at their drums while they play, he and Devon play together until Shawn drops a stick. At this point, Dr. Lee comes over and starts playing with Devon, until Devon drops a stick. The drum stick falls from Devon's hand and bounces around on the field. In the next shot, Dr. Lee is talking to Devon, neither has moved, but now Devon has both sticks in his hand.
Factual error: The whole movie shows methamphetamine constricting their pupils. Methamphetamine is a central nervous system stimulant which dilates the pupils - the exact opposite of what is shown.
Factual error: When Ellen gets married in 1907 she is 20, but when she disappears in 1950 she is 70.
Audio problem: When John rips the phone out of the wall, when it hits the floor it makes a bell sound even though its a cordless phone.
Factual error: Otisville Prison was not in the direction Monty's father was driving. He said he would take the Henry Hudson Parkway north and later continue on the Taconic Parkway. The Taconic runs due north toward Massachusetts on the east side of the Hudson River. Otisville is 30 miles west of the Hudson.
Revealing mistake: When Igby and his brother are removing the plastic bag from Mimi's head, her eyes blink.
Continuity mistake: Before Alice enters the building, you can see part of her newspaper sticking out of her bag - the area that is visible just contains text. After she enters the building, there is another shot of her from behind, and now the paper is showing part of a picture and the barcode. (00:06:15)
Continuity mistake: When Hundert packs up his stuff from the classroom he puts the Shutruk-Nahunte plaque in a box, with half of it sticking out and the inscription pointing outside. Later, when we see the box in his room, everything is the same only the plaque has been turned around. (01:09:10)
Continuity mistake: At the beginning of the film, the little boy has big brown eyes. 19 years later, when the boy is shown as an adult in the diner, he has big blue eyes.
Continuity mistake: Ray comes to Buck's hotel room with the stolen disk containing the revised speech. At the shot when Buck is sitting at the computer reading the speech, he has a wedding ring on. Buck isn't married.
Factual error: An old man appears with children following him. This is supposed to be pedagogue Janusz Korczak. It appeared as if he was just wearing a suit and a Jewish arm band. In the Warsaw Ghetto, Mr. Korczak never wore an arm band and wore his WWI Polish Army Uniform, both as acts of defiance. He was beaten and almost put to death (he had connections) for not wearing an arm band so having one on in the movie is inaccurate.
Visible crew/equipment: After Matt finds out that Nicole is engaged, he goes running through the streets. When he goes running past a glassed store display, you can see the reflection of a white van with the sliding passenger door open and a cameraman. (00:14:00)
Plot hole: The dead young girl who wears white has hemophilia (uncontrollable bleeding), and her mother states that she's scared of all sharp metal objects (scissors, etc.), yet she goes to play in an old abandoned steel mill all the time.
Continuity mistake: During the scene when Van and his friends are riding in Van's golf cart, just after Van has sex with the secretary, the guy in the back is seen being licked on the face by the bulldog. When the camera cuts to Van he's not being licked. When the camera cuts to Van's assistant he's being licked again. This happens over and over. (00:15:53)