Factual error: When the protagonists arrive to Patmos, latitude and longitude are switched the other way around at 26°489 and 37°411. Moreover, that's not Patmos, but Anydro Patmou, an uninhabited islet unlike what is shown here.
Factual error: The Kiss of the Dragon acupuncture point, known as "Point 15," is in a delicate area of the spinal column, a little below the second cervical vertebra. It's a definite knock-out target in fighting, and it can even be a lethal target. But Jet Li's explanation that it somehow prevents blood from flowing away from the brain is pure nonsense.