
Jack Walsh: Here come two words for you: shut the fuck up.

Carlos: You son of a bitch! How could you do this? Friendship is the only choice in life you can make that's yours! You can't choose your family, God damn it - I've had to face that! And no man should be judged for whatever direction his dick goes - that's like blaming a compass for pointing north, for Christ's sake! Friendship is all we have! We chose each other. How could you fuck it up? How could you make us look so bad?

Roger Rabbit: No! Not my Jessica! Not pattycake! It can't be! It just can't be! Jessica's my wife! It's absolutely impossible! Jessica's the love of my life. The apple of my eye. The cream in my coffee.
Eddie Valiant: Well you better start drinking it black, Acme's taking the cream now.

Jane: How about a rain check?
Frank: Well, let's just stick to dinner.

Janet Colgate: Fellas, last year I made 3 million dollars, but your 50 thousand was the most fun. Are you ready? Then let's go get 'em.

Otto: Don't call me stupid.
Wanda: Oh, right, to call you stupid would be an insult to stupid people! I've known sheep that could outwit you. I've worn dress with higher IQ's. But you think you're an intellectual, don't you, ape?
Otto: Apes don't read philosophy.
Wanda: Yes they do, Otto, they just don't understand it. Now let me correct you on a couple things, okay? Aristotle was not Belgian. The central message of Buddhism is not "every man for himself." And the London Underground is not a political movement. Those are all mistakes, Otto, I looked them up.

Mrs. Pell: If you're ever in Des Moines, don't send me a postcard.

Det. Samuel 'George' Francisco: You humans are very curious to us. You invite us to live among you in an atmosphere of equality that we've never known before. You give us ownership of our own lives for the first time and you ask no more of us than you do of yourselves. I hope you understand how special your world is, how unique a people you humans are. Which is why it is all the more painful and confusing to us that so few of you seem capable of living up to the ideals you set for yourselves.

Danny McGavin: Is 21st street on our list?
Bob Hodges: Nah. Poor fuckers are professional victims. Get their ass kicked constantly. Kind of a mixed gang. You got Diamond street there, the ville, and the projects on the west so they gotta fight their way in and fight their way out.
Danny McGavin: They're fucked, huh?

Harry Callahan: Oh you can set yourself into a bonfire and we'll break out the marshmallows and the weenies but you ain't gonna be on News at Eleven.

Sgt. Moses Hightower: Sir, I realize this is your jurisdiction. But if there is a rescue attempt, we would like to volunteer.
Capt. Thaddeus Harris: Commissioner Murdock, I couldn't agree more. I think it is vital that the rescues know Commandant Lassard intimately. Now, I can vouch for the abilities of these officers. After all, I trained them myself.
Sgt. Larvell Jones: Must be the drugs.

Wyatt Earp: It's all true, give or take a lie or two.

Vermeer: What do you think she meant when she said a huge black monster with giant claws?
Eric Visser: I don't know, but I hope your mother-in-law has an alibi.
Vermeer: UGH.