Trivia: The show was filmed in an actual prison (now unused) in Joliet. The death row cell used for Lincoln Burrows is the actual death row cell that held serial killer John Wayne Gacy.
Trivia: In the opening credits there is a shot of a girl standing alone on the corner of a street. This was taken from the Buffy episode "Anne", when Buffy was staying in Los Angeles.
Days of Future Past: Part 1 - S1-E11
Trivia: After Bishop travels into the past, he hears one kid telling another that they will be playing the new Punisher game "Assassin." When the Punisher was first being developed, he was originally going to be called The Assassin.
Trivia: The man Reacher passes in the diner at the end of the episode who says "excuse me" is the author of the Jack Reacher novels, Lee Child.
Trivia: They keep guessing the next game, however clues are hiding in plain sight. The illustrations on the dormitory walls depict all the games, from "Red Light, Green Light" to the final match of Squid Game.
Trivia: X-X "The Lost Episode": Some other character cameos in the concerto audience include the two English ladies talking about fish in "Revolution", and Dr. Victor Payten, his interviewer, and the soap opera character Rebecca from "Episode 257-494".
Trivia: Lou Diamond Phillips made two appearances on the show, as Mark DeSalvo, the security chief where Victor Drazen is being held. Philips and star Kiefer Sutherland are known for having worked together in Young Guns and Young Guns 2.
Trivia: When the Quirks uses their noses to play a song to get rid of Koopa for good, they play the theme song from the video game The Legend of Zelda.
Forever Red - S1-E34
Trivia: This episode featured an appearance by every Red Ranger, with the exception of Steve Cardenas, who played Rocky in series 2, 3, and 4.
Trivia: A film reference to Star Trek: First Contact: Archer says something about a group of cybernetic creatures (The Borg), that tried to stop Cochrane from launching his mission into space that was stopped by a group of humanoids, that were also from the future (USS Enterprise NCC 1701-E).
Insect Inside / Powerpuff Bluff - S1-E1
Trivia: In "Powerpuff Bluff", Dexter makes a cameo appearance when the kindergarten kids have a nap time.
Trivia: Though Dirk Benedict is well known for playing Templeton "Faceman" Peck he didn't play the role in the pilot. The role in the pilot was played by Tim Dunigan.
Trivia: Rain Robinson has a model of a DY-100 on the window sill in her office. In 1996 (also the year this episode is set), Kahn left Earth in the SS Botany Bay, a DY-100 class starship.
Trivia: Gaspard Ulliel, who portrays Anton Mogart, was involved in a fatal skiing accident the day after the trailer for this series debuted. The third episode is dedicated to his memory.
Visitors From Beyond the Stars - S1-E18
Trivia: The Time Tunnel Homing Beacon used in "The Revenge of Robin Hood" episode is hanging on the bulkhead by the door of the aliens' spaceship.
Trivia: The Widow Twanky was portrayed by Michael Hurst although he would be credited as Edith Sidebottom.
Crisis on Earth-X, Part 3 - S4-E8
Trivia: Supergirl says to her doppelganger "General, can you step outside." That line was said by Superman in Superman II.
Trivia: Nate's dad, played by Thomas F. Wilson, says "let's make like a tree and leave", to which Nate replies "I'm not sure that's how it goes." Thomas F. Wilson famously played Biff in the Back to the Future films, who frequently got that saying wrong.