Continuity mistake: When Peter and Debra are approaching Dr. Connors' office, the nameplate on his door misspells his name as "DR. CURT CONNeRS". After they have entered the lab, the nameplate is shown to have the correct spelling. (00:06:10)
Doctor Octopus: Armed and Dangerous - S1-E4
Continuity mistake: Doc Ock's left glove briefly disappears during his second fight with Spider-Man, and Jameson's pants are briefly his jacket's color during that fight.
The Menace of Mysterio - S1-E5
Continuity mistake: Mysterio sounds cold and calculating in this episode. Yet in later ones he sounds different despite being voiced by the same actor.
The Menace of Mysterio - S1-E5
Continuity mistake: When Mysterio's unconscious he's in his costume. When Spider-Man leaves him webbed up he's wearing street clothes. But when he's shown on the headlines of the Daily Bugle he's back in his Mysterio costume.
The Sting of the Scorpion - S1-E6
Continuity mistake: The Scorpion gets bigger here, his eyes turn yellow, he gets fangs, his skin becomes sickly looking, and his fingertips resemble claws. Yet later on in later episodes he's missing all of that.
Continuity mistake: Kraven's arm band that he wears on his upper right arm switches to his left one briefly after he fights Spider-Man for the first time.
Answer: Yes. Many things that would have been in the sixth season would have had Norman Osborne returning from limbo and reclaiming the title of the Green Goblin, Richard Fisk, the son of "The Kingpin" Wilson Fisk would return as a crime lord known as "The Rose", Ghost Rider would have appeared to help Spider-Man stop Dormammu from returning to Earth and Madame Web and Spider-Man would rescue Mary Jane from limbo.