Deliberate mistake: Though by 1964 it was already suspected (and later confirmed by Mariner IV) that Mars has an atmosphere humans can't breathe and temperatures too low for humans to tolerate, Merritt and his crew are here exploring the planet sans spacesuits. This was "fudged" because space helmets A)are expensive, B)reflect cameras, and most importantly, C)obscure the actors' faces. (00:24:00)
Continuity mistake: When she's inside the giant test tube, Amanda raises her arms over her head. In the very next shot, with no time for her to have moved that fast, her arms are straight down and held rigidly at her sides. (00:36:15)
Continuity mistake: In the lab, Anderson collapses with his arms crossed above his head. When the shot cuts, his arms are suddenly uncrossed. (00:21:30)