Continuity mistake: Airwolf goes from normal flight to combat mode and back several times per episode when it's supposed to be in passive flight.
Continuity mistake: Flight scenes and especially dog fights seem to have no continuity at all. Altitude changes from scene to scene between extreme low-level to altitudes above 10,000 ft. and back. Airwolf's weapon bays are open, then closed, etc.
Answer: No truth serum has proven to make a person tell the truth. Regarding capturing Mace, and forcing him to tell him where St. John is by water boarding him, People subject to torment such as water boarding are not likely to tell the truth, so Mace would probably lie.