Nicky and/or Alexander - S5-E11
Factual error: This episode takes place right after Jesse has had his appendix surgery. If he has just had that type of surgery he wouldn't be doing anything yet. It takes several weeks to recover from this type of surgery and he would most likely be tired and be resting a lot.
Chosen answer: The first time was in the first season, episode 19 "The Seven-Month Itch", the second was in the fourth season, episode 1 "Greek Week", the third time was in the fifth season, episode 19 "The Devil Made Me Do It" and finally in the very last episode of the series, "Michelle Rides Again", season 8 episode 23.
jennibee