The Calzone - S7-E20
Factual error: When Jerry gets a speeding ticket, he asks Nicki to give the officer the registration. She gets a large piece of white paper from the glove compartment. That's what car registrations look like in California, where the show was produced. In New York, where it's supposed to take place, car registrations are the size of a driver's license, and are usually kept in the driver's wallet.
Chosen answer: George does mention his brother in the episode "The Parking Space". They actually really never mention anything that contradicts the fact he had a brother though, it just isn't mentioned.