Continuity mistake: When Tom Kirkman visited the man who killed his wife in prison in S2E10, he sat down for the conversation. In this episode, when the surveillance video of him leaks, it shows him having the conversation whilst standing.

Designated Survivor (2016)
1 continuity mistake in The Final Frontier - chronological order
Starring: Kiefer Sutherland, Natascha McElhone, Kal Penn, Adan Canto, Italia Ricci

Character mistake: In the 11/14/2005 US Army Rangers report about Peter MacLeish, the word captain right under MacLeish's signature is misspelled "captian."
Tom Kirkman: D.C. police called the White House switchboard, wanted to confirm that you worked here. What happened this morning?
Seth Wright: What happened in Michigan. What always happens. When people don't know who their enemy is, they start with people who look like me.
Question: Why did Lyor, Mike, Brenda, Hookstaten, and Chuck randomly disappear from the series?
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Answer: It's a recurring theme on the show. Characters come and go depending on the storyline. General Cochrane, Tyler Richmond, Abe Leonard, etc.