Continuity mistake: Intro Mission 4: After Sue meets up with Reed, she uses her shield to protect him through the laser wall. Reed hacks the laser wall to allow her though which leads to an in-engine cutscene and ends the mission. It doesn't matter where you have Sue standing before he hacks the door, Sue will appear in the exact same spot far from the door and walk to Reed.
Continuity mistake: Brooklyn Mission 1: After the second save of Yancy Street gang members climb over the fence and you take out the last one, Alicia just vanishes into thin air. You can even have the camera on her when it happens. Just poof, she's gone.
Revealing mistake: Intro Mission 5: In the cinema cut scene after the mission, Reed and Victor being talking. Reed's eyes are not looking at Victor, but to the left of him.
Continuity mistake: Intro Mission 5: Once Ben uses the finishing move on the Ultra Security Bot, the cut scene shows him slam it around then throw it through the wall to the outside. Ben is standing in the center of the room. But then he says "What the hell is happening to me!?" and instantly he is standing next to the hole he just made in the wall.
Other mistake: Intro Mission 5: After the other three convince Ben to open the door, the button mashing minigame starts. Once it ends, Ben forces the door open. The other three are already instantly traveling through the door almost before he can even get them lifting, reacting way too soon. And from standing still to a full on sprint no less.
Audio problem: Intro Mission 5: As the Ultra Security Bot appears, the doors lock down in Ben's room and the other three run up on the other side, trying to get him to open it. Reed speaks a line after Ben tells Sue he can't let her see him like this. His lips don't move nor does he go into his talking animation when saying this.
Bug: Intro Mission 4: After Sue and Reed meet up, you can use Sue to put a shield around Reed so he can walk through a laser wall. Touching the laser wall will hurt either character 1% and knock them back. But if you shield Reed and then have him stand in the lasers and the shield wears off, the lasers won't hurt Reed. He is just standing there with the lasers going through him. But the moment you touch the analog stick, Reed is instantly hurt and flies back out of the lasers.
Other mistake: Intro Mission 4: In the room where Sue meets up with Reed, the room he comes out of seems pointless. The room inside when looking through the glass windows of the door, you can see no windows or doors inside the room. The only thing in there is what appears to be a sink, suggesting it is a bathroom. But that is the only thing in the room... A sink. Also, when you go into the room and look through those windows before defeating the robot, Reed is not inside. Yet after you destroy the robot, he suddenly comes out of that room. But there are no windows or doors in that room. He just suddenly appeared in there to come out.
Revealing mistake: Intro Mission 4: If you get Sue next to a wall and move the camera around so it forces a close up, you can see Sue's hair is incomplete. Especially towards the back, there being gaps in the texture showing empty space. This is fixed in later levels after her character model changes to her in her Fantastic 4 suit.
Continuity mistake: Intro Mission 3: After the nurse screams and runs away, a flying security drone is seen out the door with its back to Johnny. In the previous mission, the flying drones would have the animation of turning around. But this one, before you are given control of Johnny, turns around instantly. There is no animation to it. Its back is to you, then instantly it's facing you and moving towards you.
Continuity mistake: Intro Mission 3: When the mission starts, a nurse is in Johnny's room at the monitor. She turns around and screams as she sees Johnny on fire. He shakes his hands and head as he is right next to the bed. It cuts and suddenly he is now in the middle of the room and the nurse is suddenly away from the monitor right next to him and takes off running as he says "Wait, I'm okay! Weirdly... I'm okay."
Other mistake: Intro Mission 3: In the hallway where the patient gets smacked by a robot and then screams "Freaks and robots!?" there are some double doors on the right side of the hall. Looking through the windows of the doors, you can see an absolutely pointless room. No other doors, no windows, not big enough to be a closet or for really even a person to stand it. It's just there. Two pointless rooms in this hallway.
Other mistake: Intro Mission 2: In the room after you hack the security drone, there is a fireplace. A double door is just to the left of the fire place and has glass windows. If you look though the windows, you can see a room with no windows or doors, and is completely empty. The room is only about 6 feet by 10 feet, and is absolutely pointless. It is not a closet.
Other mistake: Intro Mission 2: The security drone Reed hacks has a health bar the same as the enemy drones. It can take hits better though and is tougher than the enemy ones, taking several hits. But after you clear the third room, he rushes over and opens up another door, and another regular enemy drone rushes him and hits him. Even with a full bar of health, this single punch destroys you security drone in one hit. And if you hit that drone before it has the chance to hit your security drone, yours gets destroyed anyway with nothing even hitting it.
Other mistake: Intro Mission 2: After Reed hacks a security drone to help him, it rushes over to open a locked door. It goes through the motions of punching in keys on a pad to open it. But if you look, he is using the animation of just punching, and he is punching the air to make the door open. His hand is not even close to the control pad, about a foot and a half from it even.
Other mistake: Intro Mission 2, 3 & 4: Most of the destructible objects you can jump over and on. Except for some reason the bed. The beds in the hospital have an invisible wall around them preventing you from jumping over or on them. Yet once you destroy the bed, you can go through that spot no problem. Ben in Intro Mission 5 is the exception to this rule, destroying the bed as he jumps on it.
Continuity mistake: Intro Mission 2: After Reed unlocks the second hacking minigame, a security drone steps out and befriends him, thinking he is Victor Doom. It steps out and is facing forward. It cuts to the security bot talking to Reed and suddenly it has turned 90 degrees to face Reed in an instant.
Revealing mistake: Intro Mission 2: Lots of the destructible objects in the hospital can be broken simply by just jumping on them. Some of these objects are large plant pots with a small green tree in them. When you jump at them, the foot only has to just touch a leaf of the plant, and it causes the whole vase to shatter.