Continuity mistake: Level 2 "Bartman Begins" cutscene: When the game instruction manual appears in front of Bart, with Homer on the front cover and a blue back cover, the manual's spine is at the left and it opens at the right, but when Bartman explains to Homer that he's now a superhero with awesome powers, the manual's spine is now at the right and it opens at the left.
Continuity mistake: Level 2 "Bartman Begins" cutscene: After Marge confiscates Bart's video game, when Bart complains about "nothing to play" we see the corner of the museum across the street and there are no crosswalk lines, nor is there a fire hydrant, but when Bart starts reading the game instruction manual there's a red fire hydrant at the corner as well as white crosswalk lines, then when Homer appears they vanish again.
Continuity mistake: Level 2 "Bartman Begins" cutscene: After Skinner's confession, when Wiggum arrives at the museum with Eddie and Lou, note Wiggum's red tie clip changes to grey then back to red, at least three times.
Continuity mistake: Level 4 "Lisa the Tree Hugger" cutscene: When Bart and Lisa are at the front gate of Auntie Nature, note the direction of the blade points on the doors are going clockwise, but in a few closeups the blade points are going anti-clockwise.
Continuity mistake: Level 4 "Lisa the Tree Hugger" cutscene: When Mr. Burns tells Smithers about his plan to cut down Springfield's forests, in the first overhead shot we see books and a telephone directly beside the desk pad, but when Smithers tells Burns it's a great idea that area of the desk is empty.
Continuity mistake: Level 5 "Mob Rules" cutscene: When Lisa shouts that they're being invaded Marge is wearing the baby carrier with Maggie, but in the exterior shot of the entire house Marge is not wearing the baby carrier, note the two shoulder straps and waist strap are gone, then Marge is babywearing again in following shots. Also note that when Bart tells them about their "super responsibilities" the doorbell has vanished.
Continuity mistake: Level 5 "Mob Rules" cutscene: There's an exterior shot of the Simpson house and their neighbor's house right before Homer tells his family that it was greatest day of his life. After Bart tells his family they should "go kick some alien butts," there's another shot of the houses, and the Simpson house is missing its antenna, mailbox, etc., and the style of the neighbor's house has changed, note its windows and roof.
Continuity mistake: Level 5 "Mob Rules" cutscene: When Martin runs out of Sequel Stop with his new game he stops Ned, and in the first shot Ned's car does not have an antenna, but when Martin pulls Ned out of the car suddenly there's an antenna at the left side of the windshield, then as Martin drives away the antenna is now at the right side of the windshield.
Continuity mistake: Level 5 "Mob Rules" cutscene: When Marge reads the newspaper and Martin runs out of Sequel Stop with his new car-jacking game, there's a row of zebra concrete barriers behind the church, but when Martin pulls Ned out of his car and starts to drive off all those barriers have vanished, then they reappear again.
Continuity mistake: Level 9 "Invasion of the Yokel-Snatchers" cutscene: When Cletus tells the aliens that he spent all day clipping coupons for a "flat screen magic picture machine," we see the building behind him has nothing on its roof, but in the next shot a huge billboard has suddenly appeared on that building's roof.
Continuity mistake: Level 12 "Grand Theft Scratchy" cutscene: After Senator Clinton congratulates Marge and Lisa for their great work a large sign falls on her, and when the bag appears with the keycard inside, in the closeup the bag's strap is lying at the back of the bag under its flap, but in the next shot that strap is now lying on the opposite side of the bag, at the front, and the bag's position on the sidewalk changes as well.
Continuity mistake: Level 16 "Game Over" cutscene: When Bart grabs the save games and threatens to destroy it, we see the front labeled "Memo: Planet Earth..." and the back is blank, then when Bart holds it up the front is facing forward, but in the next shot the label faces the opposite way, note Bart's thumb.
Continuity mistake: Bartman Begins: Whilst Bart is reading The Simpsons Game manual, the shot is panning around him. In the background, there is a lamp post visible on the corner of the street. When Homer enters the scene later on, the lamp post has changed design.
Continuity mistake: Invasion of the Yokel Snatchers: Whilst Homer and Bart are watching the citizens being taken into the spaceship and Homer is asking where mall security is, there is a water fountain visible in the far background, and there is no-one standing next to it. The shot then cuts to the water fountain, where an alien is now beside it.
Continuity mistake: Bargain Bin: When the mothership flies over the Simpson house, Bart says this must be the level boss for this part of the game, at which point Homer puts on a pair of glasses to look busy. The mothership then starts firing on them and the family start running. When the shot cuts back to them after being fired at, the glasses Homer was wearing have disappeared.
Continuity mistake: Big Super Happy Fun Fun Game: After Milhouse emerges from the water, Lisa says to him, "Knock it off Milhouse, we know it's you" and she has her right hand raised pointing at him. When the shot cuts, her hands are at her side.
Continuity mistake: Big Super Happy Fun Fun Game: When Homer and Lisa are talking with Milhouse in the opening cutscene, Homer and Lisa are standing on the ground about a few feet away from the ocean, but in the shot where Milhouse says "But I'm so huge", Homer and Lisa are suddenly a much further distance from the ocean.
Continuity mistake: Big Super Happy Fun Fun Game: When Homer says to Milhouse "Hey, the girl said she's not interested. Beat it loser", Lisa is standing next to Homer, slightly behind him, but in the next shot, Lisa is suddenly standing slightly in front of Homer.
Continuity mistake: Big Super Happy Fun Fun Game: In the opening shot of the ending cutscene, an overview shot is of Homer and Lisa standing in front of the huge toilet. They are standing in some mud in the overview angle, but when the shot cuts to a closet angle, they are suddenly standing on the ground, away from the mud.
Continuity mistake: Big Super Happy Fun Fun Game: When Homer and Lisa insert the three Sparklemon into the coin slots, Mr. Sparkle rises and the area where Homer and Lisa are standing and where the coin slots are located can be seen in the shot of Mr. Sparkle rising out of the giant toilet. They are seen standing on the left hand side of the giant toilet, but when Mr. Sparkle "cleans" the village, the giant toilet can be seen in shot, but Homer and Lisa are nowhere in sight.
